Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lupus. 2013 Oct;22(12):1251-8. doi: 10.1177/0961203313497416.
Ischemic stroke is increased in systemic lupus erythematosus (SLE) patients. The differential diagnosis of stroke in SLE is complex. Transient ischemic attack and ischemic stroke share pathophysiologic mechanisms, but prognosis may vary depending on severity and cause, and definitions are dependent on the timing and extent of the diagnostic evaluation. In SLE patients with a history of transient ischemic attacks, stroke occurred in 57%. Cerebrovascular events account for 20% to 30% of deaths in patients with SLE. In SLE, both disease-specific and traditional stroke risk factors are important.
系统性红斑狼疮（SLE）患者的缺血性脑卒中发病率增加。SLE 患者脑卒中的鉴别诊断较为复杂。短暂性脑缺血发作和缺血性脑卒中具有共同的病理生理机制，但预后可能因严重程度和病因不同而有所差异，且定义取决于诊断评估的时间和范围。在有短暂性脑缺血发作病史的 SLE 患者中，有 57%发生了脑卒中。在 SLE 患者中，脑血管事件占死亡人数的 20%至 30%。在 SLE 中，疾病特异性和传统的脑卒中危险因素都很重要。
