State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China, and Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Org Lett. 2013 Oct 18;15(20):5286-9. doi: 10.1021/ol402515s. Epub 2013 Oct 7.
The Ru(II)-catalyzed ortho-C-H amination directed by a weakly coordinating amide auxiliary with O-benzoyl hydroxylamines at room temperature has been achieved. This reaction is compatible with heterocycles including pyrazole, thiophene, benzothiophene, furan, benzofuran, and indole.
室温条件下，通过弱配位酰胺导向基团实现了 Ru(II)催化的邻位 C-H 胺化反应，使用 O-苯甲酰基羟胺作为胺化试剂。该反应能够兼容包括吡唑、噻吩、苯并噻吩、呋喃、苯并呋喃和吲哚在内的杂环化合物。
