Lebanese American University, School of Arts and Sciences, Department of Natural Sciences, PO Box 36, Byblos, Lebanon.
Appetite. 2014 Jan;72:1-7. doi: 10.1016/j.appet.2013.09.023. Epub 2013 Oct 4.
Tragopogon porrifolius (white salsify) is an edible plant commonly used in folk medicine in Lebanon and neighbouring countries. This study investigates the effect of the aqueous extract of the aerial part of T. porrifolius on lipemia and appetite regulation using a rat model. Food intake, abdominal fat percentage, blood lipid profile, liver weight and liver enzymes were assessed following 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg body weight) in standard high-carbohydrate and high-fat dietary conditions. In a separate study, the short term effect of a preload of T. porrifolius extract on food intake was evaluated. Results showed that consumption of the plant extract for a period of four weeks resulted in a marked improvement of the lipid profile (triglycerides, total cholesterol, LDL and HDL cholesterol). Body weight, food intake and intra-abdominal fat were also lower in animals given the plant extract (100 and 250 mg/kg). In addition, T. porrifolius extract preload produced a dose dependent decrease in food intake observed over 24h. The intake of T. porrifolius aqueous extract therefore improved lipemia and increased satiety in rats with no visible adverse effects.
婆罗门参（白婆罗门参）是一种可食用植物，在黎巴嫩和邻国的民间医学中被广泛应用。本研究采用大鼠模型，考察了婆罗门参地上部分的水提物对脂血症和食欲调节的影响。在标准的高碳水化合物和高脂肪饮食条件下，通过饮用水（50、100 或 250mg/kg 体重）摄入提取物 4 周后，评估了食物摄入量、腹部脂肪百分比、血脂谱、肝重和肝酶。在另一项研究中，评估了婆罗门参提取物的预负荷对食物摄入的短期影响。结果表明，植物提取物的持续摄入 4 周可显著改善血脂谱（甘油三酯、总胆固醇、LDL 和 HDL 胆固醇）。给予植物提取物的动物的体重、食物摄入量和腹内脂肪也较低（100 和 250mg/kg）。此外，婆罗门参提取物预负荷可在 24 小时内观察到剂量依赖性地降低食物摄入量。因此，婆罗门参水提物的摄入可改善大鼠的脂血症并增加饱腹感，且无明显不良反应。
