Aagaard Mark Faurholt, Niebuhr Malene Hartwig, Jacobsen Jens Duelund, Krøyer Nielsen Kurt
Department of Urology, Frederiksberg Hospital , Frederiksberg , Denmark.
Scand J Urol. 2014 Jun;48(3):290-4. doi: 10.3109/21681805.2013.840857. Epub 2013 Oct 9.
The aim of this study was to evaluate transurethral microwave thermotherapy (TUMT) in the treatment of chronic urinary retention due to benign prostatic hyperplasia (BPH) in patients unsuitable for surgery.
The study enrolled 124 patients with chronic urinary retention due to BPH. The median age was 80 years (61-92 years). Of the enrolled patients, 77 (62%) were assessed by an anaesthesiologist as being unsuitable for surgery owing to cardiac, pulmonary, neurological or other diseases. Overall, 115 patients (93%) had an indwelling catheter. The remaining nine patients (7%) performed clean intermittent self-catheterization. The treatment was performed under local anaesthesia in the outpatient department using the ProstaLund Coretherm Device. At the 6-month follow-up, the Danish version of the International Prostate Symptom Score (DAN-PSS), postvoiding residual volume and urinary peak flow were measured. Improvement in quality of life was also registered.
The success of TUMT was assessed by looking at the percentage of patients relieved of their catheter and by the improvement in quality of life. Overall, 77% of patients were relieved of their catheter and 79% reported an improvement in their quality of life.
In this study, both the median age and the percentage of patients unsuitable for surgery were larger than in previous studies. Despite this, TUMT relieved 77% of their catheter and 79% reported an improvement in their quality of life. This study shows that TUMT is an effective treatment for patients unsuitable for surgery and with chronic urinary retention.
本研究旨在评估经尿道微波热疗(TUMT)对因良性前列腺增生(BPH)导致慢性尿潴留且不适于手术的患者的治疗效果。
本研究纳入了124例因BPH导致慢性尿潴留的患者。中位年龄为80岁(61 - 92岁)。在纳入的患者中,77例(62%)经麻醉医生评估因心脏、肺部、神经或其他疾病不适于手术。总体而言,115例患者(93%)留置了导尿管。其余9例患者(7%)进行清洁间歇性自家导尿。治疗在门诊局部麻醉下使用ProstaLund Coretherm设备进行。在6个月随访时,测量丹麦版国际前列腺症状评分(DAN - PSS)、排尿后残余尿量和尿流峰值。还记录了生活质量的改善情况。
通过观察拔除导尿管的患者百分比以及生活质量的改善情况来评估TUMT的治疗效果。总体而言,77%的患者拔除了导尿管,79%的患者报告生活质量有所改善。
在本研究中,中位年龄和不适于手术的患者百分比均高于以往研究。尽管如此,TUMT使77%的患者拔除了导尿管,79%的患者报告生活质量有所改善。本研究表明,TUMT对于不适于手术且患有慢性尿潴留的患者是一种有效的治疗方法。