1 Centre for Complementary Medicine Research, University of Western Sydney , Penrich, New South Wales, Australia .
J Altern Complement Med. 2014 Feb;20(2):103-12. doi: 10.1089/acm.2013.0142. Epub 2013 Oct 8.
This study examined the feasibility of conducting a randomized controlled trial of acupuncture compared with an active control in an inpatient setting, to examine individuals' experience of the interventions, clinical outcomes from the trial, and to integrate data to explain the trial findings.
This was a pilot randomized controlled trial with in-depth interviews with trial participants.
The study was conducted at a private medical facility in Sydney, Australia.
Twenty-six (26) patients with anorexia nervosa who were medically stable were the subjects.
Treatment as usual was administered, and the intervention was delivered twice a week for the first 3 weeks, followed by weekly treatment for three weeks. The acupuncture group received acupuncture at the points Hegu (LI4), Zusanli (ST36), Neiguan (PC6), Taichong (LR3), Yanglingquan (GB34), and additional points based on the Traditional Chinese Medicine diagnosis. The control group received acupressure and massage. Acupressure involved consciously and gradually directing pressure to the center of the point being worked on.
Clinical outcomes were measured at baseline and at 6 weeks following completion of the intervention. The primary outcome measure was body-mass index (BMI), and secondary outcomes included eating disorder psychopathology, anxiety, and depression. A semistructured interview was conducted asking questions about their interaction with the practitioner, what happened, how they felt, whether it made them feel differently, and what they attributed any change to.
We found timely recruitment with the population recruited within a 5-month period. Study dropouts were 23% and treatment compliance was moderate, but acceptable for this challenging population. Participants in the control group demonstrated reduced eating concerns. Participants described both interventions positively, and experienced a sense of calmness and relaxation.
Acupuncture and acupressure and massage may improve the patient's subjective sense of wellbeing, and further research is needed.
本研究旨在检验在住院环境下进行针灸与活性对照随机对照试验的可行性，以检验干预措施的可操作性、试验的临床结果，并整合数据解释试验结果。
这是一项具有深入访谈的试点随机对照试验。
研究在澳大利亚悉尼的一家私人医疗设施进行。
26 名患有神经性厌食症且身体稳定的患者是研究对象。
给予常规治疗，前 3 周每周治疗两次，然后每周治疗 3 周。针灸组接受针刺合谷穴（LI4）、足三里穴（ST36）、内关穴（PC6）、太冲穴（LR3）、阳陵泉穴（GB34）和根据中医诊断的其他穴位。对照组接受指压和按摩。指压涉及有意识地逐渐将压力施加到正在按压的穴位中心。
在基线和干预完成后 6 周时测量临床结果。主要结果测量指标是体重指数（BMI），次要结果包括饮食障碍病理、焦虑和抑郁。进行了半结构化访谈，询问参与者与从业者的互动、发生的事情、他们的感受、是否让他们感觉不同以及他们将任何变化归因于什么。
我们发现，在 5 个月的时间内，及时招募到了研究对象。研究脱落率为 23%，治疗依从性中等，但对于这一具有挑战性的人群来说是可以接受的。对照组的参与者表现出饮食担忧减少。参与者对两种干预措施都给予了积极评价，并体验到平静和放松的感觉。
针灸和指压按摩可能会改善患者的主观幸福感，需要进一步研究。
