Nerschbach V, Eule J C, Eberle N, Höinghaus R, Betz D
Small Animal Hospital, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Small Animal Clinic, Faculty of Veterinary Medicine, Freie Universität, Berlin, Germany.
Vet Comp Oncol. 2016 Mar;14(1):58-66. doi: 10.1111/vco.12061. Epub 2013 Sep 17.
Ocular manifestations of lymphoma are described in humans and dogs but rarely in cats. In this prospective study, cats with newly diagnosed and treatment-naïve lymphoma were evaluated concerning clinical stage and ophthalmologic findings. Twenty-six cats were included. In 12 cats (48%), ocular changes were documented. Uveitis anterior and posterior were predominant findings, being present in 58% of affected individuals. Other findings included exophthalmos, corneal surface lesions and chemosis. Eight cats received chemotherapy, two of which had ocular involvement. In these two cats, a complete remission of an anterior and a partial remission of a posterior uveitis were documented. Due to the detection of ocular involvement, a stage migration from stage IV to V occurred in four patients. In the light of these findings, an opthalmological examination may be considered as an important part of staging in feline lymphoma as well as of follow-up examination in affected cats.
淋巴瘤的眼部表现已在人类和犬类中有所描述，但在猫中很少见。在这项前瞻性研究中，对新诊断且未接受过治疗的淋巴瘤猫进行了临床分期和眼科检查评估。共纳入26只猫。12只猫（48%）有眼部变化记录。前葡萄膜炎和后葡萄膜炎是主要表现，在58%的患病个体中出现。其他表现包括眼球突出、角膜表面病变和结膜水肿。8只猫接受了化疗，其中2只眼部受累。在这2只猫中，记录到前葡萄膜炎完全缓解和后葡萄膜炎部分缓解。由于检测到眼部受累，4例患者的分期从IV期升至V期。鉴于这些发现，眼科检查可被视为猫淋巴瘤分期以及患病猫后续检查的重要组成部分。
