Bouayad H, Feeney D A, Caywood D D, Hayden D W
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
J Am Vet Med Assoc. 1987 Dec 15;191(12):1610-5.
Thirteen cases of canine pheochromocytoma seen at the University of Minnesota Veterinary Teaching Hospital between 1981 and 1985 were reviewed. In 8 cases, the neoplasms were locally invasive; in the remaining cases, they were confined to the adrenal gland. Clinical signs compatible with fatal cardiovascular collapse secondary to a hypertensive or arrythmic episode were observed in 6 of 8 dogs with invasive neoplasms that died during examination or shortly thereafter. The remaining 2 dogs with invasive neoplasms had antemortem diagnoses of adrenal gland neoplasm with metastases and were euthanatized. Invasion or encroachment of the caudal vena cava in 6 dogs and encroachment of the aorta and other regional vasculature in 2 dogs were discovered at necropsy. In 5 dogs, the noninvasive pheochromocytoma was found incidentally during necropsy.
对1981年至1985年间明尼苏达大学兽医教学医院收治的13例犬嗜铬细胞瘤病例进行了回顾。8例肿瘤呈局部浸润性生长；其余病例肿瘤局限于肾上腺。8例浸润性肿瘤犬中有6例在检查期间或之后不久死亡，观察到与高血压或心律失常发作继发的致命性心血管衰竭相符的临床症状。其余2例浸润性肿瘤犬生前诊断为肾上腺肿瘤伴转移，随后实施了安乐死。尸检发现6只犬的尾腔静脉受侵或受压，2只犬的主动脉和其他局部血管受侵。5只犬的非浸润性嗜铬细胞瘤在尸检时偶然发现。
