Aarthi J, Muthu M S, Sujatha S
Department of Pediatric Dentistry, Saveetha Dental College, Saveetha University, Chennai, India,
Eur Arch Paediatr Dent. 2013 Oct;14(5):289-300. doi: 10.1007/s40368-013-0088-6. Epub 2013 Oct 9.
To assess the cariogenic potential of cow's milk, human milk and infant formulas in comparison to sucrose in animal models.
Electronic search of the following databases were undertaken: PubMed-MEDLINE, MeSH and ingentaconnect. In addition, the reference lists of all eligible studies were searched. Characteristics such as animal species were used; comparisons and outcomes measured were analysed.
The search yielded a total of 13 articles of which six studies met the inclusion criteria and seven were excluded. All the six included studies used rat models for assessing the cariogenic potential of the test groups. Cow's milk was compared with sucrose in all of the six studies, reporting cow's milk to be less cariogenic than sucrose. Two studies compared human milk to sucrose and reported human milk to be less cariogenic than sucrose, but more than that of cow's milk. Although infant formulas were compared with sucrose in four studies, their cariogenic potential was a matter of some ambiguity.
The evidence suggests that cow's milk and human milk are less cariogenic than sucrose, with cow's milk being the least cariogenic. The cariogenic potential of infant formulas varied across the studies, with some being as cariogenic as sucrose.
在动物模型中评估牛奶、人乳和婴儿配方奶粉与蔗糖相比的致龋潜力。
对以下数据库进行电子检索：PubMed - MEDLINE、医学主题词表（MeSH）和IngentaConnect。此外，还检索了所有符合条件研究的参考文献列表。使用了动物种类等特征；对所测量的比较和结果进行了分析。
检索共得到13篇文章，其中6项研究符合纳入标准，7项被排除。所有6项纳入研究均使用大鼠模型评估试验组的致龋潜力。在所有6项研究中都将牛奶与蔗糖进行了比较，结果表明牛奶的致龋性低于蔗糖。两项研究将人乳与蔗糖进行了比较，结果表明人乳的致龋性低于蔗糖，但高于牛奶。虽然在4项研究中对婴儿配方奶粉与蔗糖进行了比较，但其致龋潜力存在一定的模糊性。
证据表明，牛奶和人乳比蔗糖的致龋性低，其中牛奶的致龋性最低。婴儿配方奶粉的致龋潜力在各项研究中有所不同，有些与蔗糖的致龋性相当。
