Biotechnology Research Group, Shahrood University, Shahrood, Iran.
Curr Protein Pept Sci. 2013 Dec;14(8):698-710.
Antimicrobial peptides (AMPs) are found as important components of the innate immune system (host defense) of all invertebrates. These peptides can be constitutively expressed or induced in response to microbial infections. Indeed, they vary in their amino acid sequences, potency and antimicrobial activity spectra. The smaller AMPs act greatly by disrupting the structure or function of microbial cell membranes. Here, the insect innate immune system with emphasis on inducible antimicrobial peptide properties against microbial invaders has been discussed.
抗菌肽 (AMPs) 是所有无脊椎动物先天免疫系统 (宿主防御) 的重要组成部分。这些肽可以在受到微生物感染时被组成性表达或诱导。事实上，它们在氨基酸序列、效力和抗菌活性谱方面存在差异。较小的 AMP 通过破坏微生物细胞膜的结构或功能而发挥重要作用。本文重点讨论了昆虫先天免疫系统，以及针对微生物入侵的诱导性抗菌肽特性。
