Sun Liqian, Wang Yanlei, Yang Cuiwei, Chen Ying, Wu Zhong, Yu Jianguo
Annu Int Conf IEEE Eng Med Biol Soc. 2013;2013:1021-4. doi: 10.1109/EMBC.2013.6609677.
The methods of dominant frequency and Lorenz plot are used in this study to evaluate the activation rate and the activation rate variability of cardiac signals during atrial fibrillation. An epicardial mapping system was applied to acquire the atrial electrogram of mongrel dogs. The dominant frequency and Lorenz plot of each signal from various myocardial regions of the atria were analyzed. Our results show that both a frequency gradient and a variability gradient exist in the atria and the roots of pulmonary veins. The dominant frequencies of the anterior atria are higher than the posterior ones and the activation variability of both atria was higher than those of the pulmonary veins. A combination of these two methods may provide a more comprehensive understanding of the electrophysiology mechanism associated with atrial fibrillation.
本研究采用主频和Lorenz图方法，评估心房颤动时心脏信号的激活率和激活率变异性。应用心外膜标测系统采集杂种犬的心房电图。分析来自心房各个心肌区域的每个信号的主频和Lorenz图。我们的结果表明，心房和肺静脉根部均存在频率梯度和变异性梯度。前心房的主频高于后心房，且两个心房的激活变异性均高于肺静脉。这两种方法的结合可能会更全面地了解与心房颤动相关的电生理机制。
