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丹麦同性恋者中的人类嗜T淋巴细胞逆转录病毒III型(HTLV-III)

Human T-lymphotropic retrovirus type III (HTLV-III) in Danish homosexuals.

作者信息

Lange Wantzin G, Saxinger W C, Weismann K, Gallo R C

出版信息

Acta Derm Venereol. 1985;65(3):247-50.

PMID:2411083
Abstract

Sera from 119 patients attending a venereal disease clinic in Copenhagen during May 1983 were screened for antibodies to the newly characterized and isolated retrovirus HTLV-III. Ten out of 45 (22%) homosexual patients and two out of 74 (2.7%) heterosexual patients were found to have antibodies against HTLV-III. The homosexual group (except one case that developed AIDS and died during one year observation period) contained otherwise healthy men some of which had no contact with individuals from high-risk areas and only a few sexual partners. These results strongly suggest that Danish homosexuals with only few contacts are also at risk and that sero-epidemiological studies should also include the healthy homosexual group and probably the heterosexual group attending venereal disease clinics.

摘要

1983年5月期间,对哥本哈根一家性病诊所的119名患者的血清进行了检测,以筛查针对新鉴定和分离出的逆转录病毒HTLV-III的抗体。45名同性恋患者中有10名(22%),74名异性恋患者中有2名(2.7%)被发现含有抗HTLV-III抗体。同性恋组(除1例在一年观察期内患艾滋病死亡外)其他成员均为健康男性,其中一些人与高危地区的人没有接触,且性伴侣很少。这些结果强烈表明,接触很少的丹麦同性恋者也有感染风险,血清流行病学研究也应包括健康的同性恋群体,可能还应包括就诊于性病诊所的异性恋群体。

相似文献

1
Human T-lymphotropic retrovirus type III (HTLV-III) in Danish homosexuals.丹麦同性恋者中的人类嗜T淋巴细胞逆转录病毒III型(HTLV-III)
Acta Derm Venereol. 1985;65(3):247-50.
2
Prospective study of cytotoxic T lymphocyte responses to influenza and antibodies to human T lymphotropic virus-III in homosexual men. Selective loss of an influenza-specific, human leukocyte antigen-restricted cytotoxic T lymphocyte response in human T lymphotropic virus-III positive individuals with symptoms of acquired immunodeficiency syndrome and in a patient with acquired immunodeficiency syndrome.对同性恋男性中细胞毒性T淋巴细胞对流感的反应及人类嗜T淋巴细胞病毒III型抗体的前瞻性研究。在患有获得性免疫缺陷综合征症状的人类嗜T淋巴细胞病毒III型阳性个体以及一名获得性免疫缺陷综合征患者中,流感特异性、人类白细胞抗原限制的细胞毒性T淋巴细胞反应选择性丧失。
J Clin Invest. 1985 Oct;76(4):1699-704. doi: 10.1172/JCI112158.
3
[Prevalence of antibodies against HTLV-III in various regions in Switzerland].
Schweiz Med Wochenschr. 1985 Jul 27;115(30):1048-54.
4
[HTLV-III antibodies and risk factors for healthy homosexuals in Zurich].[苏黎世健康同性恋者的人类嗜T淋巴细胞病毒III型抗体及风险因素]
Schweiz Med Wochenschr. 1985 Dec 7;115(49):1777-8.
5
Relation of HTLV-III seropositivity and lymphadenopathy.人类嗜T淋巴细胞病毒III型血清阳性与淋巴结病的关系。
Can Med Assoc J. 1985 Jul 15;133(2):111-2.
6
HTLV-III: the etiologic agent of AIDS.人类嗜T淋巴细胞病毒III型:艾滋病的病原体。
Princess Takamatsu Symp. 1984;15:301-8.
7
Immune functions in homosexual men with antibodies to HTLV-III in Finland.芬兰携带人类嗜T淋巴细胞病毒III型抗体的男同性恋者的免疫功能
Clin Exp Immunol. 1985 Apr;60(1):17-24.
8
Antibody to human lymphotropic virus type III: immunologic status of homosexual contacts of patients with the acquired immunodeficiency syndrome and the acquired immunodeficiency-related complex.抗人类嗜淋巴细胞病毒III型抗体:获得性免疫缺陷综合征及获得性免疫缺陷相关综合征患者同性恋接触者的免疫状况
Sex Transm Dis. 1987 Jan-Mar;14(1):44-7.
9
[Antibodies against human T-cell leukemia virus type III in acquired immunodeficiency syndrome and persistent lymphadenopathy].获得性免疫缺陷综合征和持续性淋巴结病中针对人类III型T细胞白血病病毒的抗体
Dtsch Med Wochenschr. 1984 Nov 9;109(45):1709-11. doi: 10.1055/s-2008-1069439.
10
HIV and HTLV-I antibody studies: pregnant women in the 1960s, patients with AIDS, homosexuals, and individuals with tropical spastic paraparesis.艾滋病毒和人类嗜T淋巴细胞病毒I型抗体研究:20世纪60年代的孕妇、艾滋病患者、同性恋者以及患有热带痉挛性截瘫的个体。
Yale J Biol Med. 1987 Nov-Dec;60(6):569-74.

引用本文的文献

1
Sequential HTLV-III antibody studies in Danish homosexual men.
Arch Dermatol Res. 1987;279(3):204-5. doi: 10.1007/BF00413259.
2
Hepatitis B in symptomless Danish homosexual men.丹麦无症状男同性恋者中的乙型肝炎
Genitourin Med. 1988 Feb;64(1):39-42. doi: 10.1136/sti.64.1.39.