Widemar L, Hellström S, Schultzberg M, Stenfors L E
Acta Otolaryngol. 1985 Jul-Aug;100(1-2):58-65. doi: 10.3109/00016488509108588.
The innervation of the tympanic membrane of the rat was investigated with respect to noradrenergic and peptide-containing nerve fibres. In sections, most of the nerves in both the flaccida portion and the tensa portion seemed to be of the small, unmyelinated types, though a few larger myelinated nerves were also found. Noradrenergic fibres, exhibiting specific catecholamine fluorescence (CA), were detected along the blood vessels in the pars flaccida and along the vascular network of the annulus fibrosus. In the pars flaccida, fibres exhibiting SP-like, VIP-like- and enkephalin-like immunoreactivity were noted. None of these peptides could be detected in the pars tensa. The exclusive localization of the oedema-provoking peptides, SP and VIP, to the pars flaccida may be of importance with regard to establishing pars flaccida as the initial site of effusion production in experimental secretory otitis media.
对大鼠鼓膜的神经支配进行了有关去甲肾上腺素能神经纤维和含肽神经纤维方面的研究。在切片中，松弛部和紧张部的大多数神经似乎都是细小的无髓神经，不过也发现了一些较粗大的有髓神经。沿松弛部的血管以及纤维环的血管网检测到了呈现特异性儿茶酚胺荧光（CA）的去甲肾上腺素能纤维。在松弛部，注意到了呈现P物质样、血管活性肠肽样和脑啡肽样免疫反应性的纤维。在紧张部未检测到这些肽中的任何一种。引起水肿的肽P物质和血管活性肠肽在松弛部的独特定位，对于将松弛部确立为实验性分泌性中耳炎积液产生的起始部位可能具有重要意义。
