Mir R, Aftalion B, Kahn L B
Arch Pathol Lab Med. 1985 Sep;109(9):867-70.
We describe a predominant extranodal involvement of unusual sites by sinus histiocytosis with massive lymphadenopathy (SHML). The patient first presented at 13 years of age with bilateral parotid gland enlargement and was discovered to have a large asymptomatic left renal mass and adjacent hilar adenopathy, histologically diagnostic of SHML. Following a left nephrectomy, he remained well with persistent parotid and lacrimal gland disease and, 20 years later, plaquelike meningeal involvement mimicking meningioma en plaque developed that was associated with reactive meningeal nests within the body of the lesion. At no time during the last 20 years has there been a recurrence of significant external nodal enlargement, and biopsy specimens of neck and intrathoracic lymph nodes have been nondiagnostic of SHML.
我们描述了1例伴巨大淋巴结病的窦性组织细胞增生症（SHML）主要累及不常见部位的结外病变。该患者13岁时首次就诊，表现为双侧腮腺肿大，发现左肾有一巨大无症状肿块及相邻肾门淋巴结病变，组织学诊断为SHML。左肾切除术后，患者腮腺和泪腺疾病持续存在，情况良好，20年后，出现类似斑块状脑膜瘤的斑块状脑膜受累，病变内有反应性脑膜巢。在过去20年中，体表淋巴结从未有过明显肿大复发，颈部和胸腔内淋巴结活检标本未诊断出SHML。
