Department of Otolaryngology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Technostics Ltd, Castle Hill Hospital, Kingston-Upon-Hull, United Kingdom.
Ann N Y Acad Sci. 2013 Oct;1300:71-79. doi: 10.1111/nyas.12237.
In patients with laryngopharygeal reflux (LPR), gastric contents exhibit retrograde flow into the upper aero-digestive tract, causing extraesophageal symptoms including chronic cough, hoarseness, indigestion, difficulty swallowing, globus pharyngis, and asthma. The following on laryngopharyngeal reflux includes commentaries on the use of patient-completed questionaires and anti-human pepsin antibodies and other non-invasive tests in diagnosis; the role of pepsin and acid in the etiologies of laryngeal cancers; and the application of proton pump inhibitor (PPI) therapy for the treatment of LPR.
在胃食管反流病（LPR）患者中，胃内容物出现反流进入上呼吸道-消化道，引起食管外症状，包括慢性咳嗽、声音嘶哑、消化不良、吞咽困难、咽部异物感和哮喘。以下是关于喉咽反流的内容，包括对患者完成的问卷和抗人胃蛋白酶抗体等非侵入性检查在诊断中的应用的评论；胃蛋白酶和酸在喉癌病因中的作用；以及质子泵抑制剂（PPI）治疗 LPR 的应用。
