Department of Oral and Maxillofacial Surgery, School of Stomatology, Peking University, Beijing, China.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Nov;116(5):556-61. doi: 10.1016/j.oooo.2013.07.011.
The aim of this study was to evaluate the results of elective neck dissection (END) versus those of observation in the treatment of squamous cell carcinoma of the maxillary gingiva.
This was a retrospective study of 129 cases.
There were 2 (4.0%) patients in the END group and 19 (24.1%) patients in the observation group who developed nodal recurrence alone. The regional recurrence rate of the observation group was 9.1% for T1 disease, 19.0% for T2, 27.3% for T3, and 40.0% for T4. Patients with stages T2 to T4 who underwent END received more survival benefit than did those in the observation group (P = .048). There were no statistical differences for patients with stage T1 disease between the 2 groups (P = .605).
This retrospective study suggests that END should be recommended as a preferred management strategy for stage T2 to T4 disease and that observation may be an acceptable alternative to END for stage T1 tumors if strict compliance with a cancer surveillance protocol is followed.
本研究旨在评估择区性颈清扫术（END）与观察在治疗上颌牙龈鳞癌中的疗效。
这是一项回顾性研究，共纳入了 129 例患者。
在 END 组中，有 2 例（4.0%）患者和在观察组中有 19 例（24.1%）患者仅发生淋巴结复发。观察组中 T1 期的局部复发率为 9.1%，T2 期为 19.0%，T3 期为 27.3%，T4 期为 40.0%。与观察组相比，接受 END 的 T2 至 T4 期患者的生存获益更多（P =.048）。两组 T1 期患者之间无统计学差异（P =.605）。
本回顾性研究表明，对于 T2 至 T4 期疾病，END 应被推荐为首选治疗策略，对于 T1 期肿瘤，如果严格遵守癌症监测方案，观察可能是 END 的一种可接受的替代方案。
