对大鼠膀胱肾上腺素能神经纤维的刺激。

Stimulation of adrenergic nerve fibres to the urinary bladder of the rat.

作者信息

Elmér M

出版信息

Acta Physiol Scand. 1975 Aug;94(4):517-21. doi: 10.1111/j.1748-1716.1975.tb05911.x.

DOI:10.1111/j.1748-1716.1975.tb05911.x

Abstract

The contraction of the rat detrusor muscle caused by electrical stimulation of the hypogastric or pelvic nerves was followed by relaxation when the nerves were stimulated for a short period. The relaxation was more pronounced when the initial contraction was reduced by atropine. It was found to be mediated by adrenergic fibres acting on inhibitory beta2-receptors. Stimulation of the hypogastric or pelvic nerves at high frequencies increased the contractile response probably via adrenergic fibres activating excitatory alpha-receptors.

摘要

电刺激大鼠腹下神经或盆神经引起逼尿肌收缩后，若短时间刺激神经则会出现舒张。当用阿托品减弱初始收缩时，舒张更为明显。发现这种舒张是由作用于抑制性β2受体的肾上腺素能纤维介导的。高频刺激腹下神经或盆神经可能通过激活兴奋性α受体的肾上腺素能纤维增强收缩反应。

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