Araujo Júnior Edward, Martins Wellington P, Rolo Liliam Cristine, Pires Claudio Rodrigues, Zanforlin Filho Sebastião Marques
Childs Nerv Syst. 2014 Jan;30(1):9-12. doi: 10.1007/s00381-013-2298-y.
The aim of this study was to determine normative data for fetal cisterna magna length (CML) measurement in a Brazilian population.
This was a retrospective cross-sectional study on 3,862 normal singleton pregnancies between the 18th and 24th weeks of pregnancy. Fetal CML was measured in the axial plane of the fetal head, at lateral ventricle level, including the cavum septum pellucidum, thalamus, third ventricle, and transverse cerebellar diameter. The anteroposterior measurement was made between the posterior border of the cerebellar vermis and the internal face of the occipital bone. To assess the correlation between CML and gestational age (GA), polynomial equations were calculated, with adjustments using determination coefficient (R2).
The mean CML ranged from 4.29±0.93 mm at 18 to 18+6 weeks to 5.58±1.23 mm at 24 to 24+6 weeks of pregnancy. There was a good correlation between CML and GA, best represented by a linear equation: CML=0.535+0.208*GA (R2=0.084).
We established normative data for fetal CML in the second trimester of pregnancy, in a large Brazilian population.
本研究旨在确定巴西人群中胎儿后颅窝池长度（CML）测量的标准数据。
这是一项对3862例妊娠18至24周的正常单胎妊娠进行的回顾性横断面研究。在胎儿头部的轴平面、侧脑室水平测量胎儿CML，包括透明隔腔、丘脑、第三脑室和小脑横径。在小脑蚓部后缘与枕骨内面之间进行前后径测量。为了评估CML与孕周（GA）之间的相关性，计算了多项式方程，并使用决定系数（R2）进行调整。
妊娠18至18 + 6周时，CML的平均值为4.29±0.93mm；妊娠24至24 + 6周时，CML的平均值为5.58±1.23mm。CML与GA之间存在良好的相关性，最佳表现为线性方程：CML = 0.535 + 0.208 * GA（R2 = 0.084）。
我们在巴西的一大群人中建立了妊娠中期胎儿CML的标准数据。
