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吞咽困难:评估与协作管理。

Dysphagia: Evaluation and Collaborative Management.

机构信息

Mayo Clinic College of Medicine and Science, Rochester, MN, USA.

出版信息

Am Fam Physician. 2021 Jan 15;103(2):97-106.

PMID:33448766
Abstract

Dysphagia is common but may be underreported. Specific symptoms, rather than their perceived location, should guide the initial evaluation and imaging. Obstructive symptoms that seem to originate in the throat or neck may actually be caused by distal esophageal lesions. Oropharyngeal dysphagia manifests as difficulty initiating swallowing, coughing, choking, or aspiration, and it is most commonly caused by chronic neurologic conditions such as stroke, Parkinson disease, or dementia. Symptoms should be thoroughly evaluated because of the risk of aspiration. Patients with esophageal dysphagia may report a sensation of food getting stuck after swallowing. This condition is most commonly caused by gastroesophageal reflux disease and functional esophageal disorders. Eosinophilic esophagitis is triggered by food allergens and is increasingly prevalent; esophageal biopsies should be performed to make the diagnosis. Esophageal motility disorders such as achalasia are relatively rare and may be overdiagnosed. Opioid-induced esophageal dysfunction is becoming more common. Esophagogastroduodenoscopy is recommended for the initial evaluation of esophageal dysphagia, with barium esophagography as an adjunct. Esophageal cancer and other serious conditions have a low prevalence, and testing in low-risk patients may be deferred while a four-week trial of acid-suppressing therapy is undertaken. Many frail older adults with progressive neurologic disease have significant but unrecognized dysphagia, which significantly increases their risk of aspiration pneumonia and malnourishment. In these patients, the diagnosis of dysphagia should prompt a discussion about goals of care before potentially harmful interventions are considered. Speech-language pathologists and other specialists, in collaboration with family physicians, can provide structured assessments and make appropriate recommendations for safe swallowing, palliative care, or rehabilitation.

摘要

吞咽困难很常见,但可能报告不足。应根据具体症状,而非其感知位置,来指导初始评估和影像学检查。看似起源于喉咙或颈部的阻塞性症状实际上可能由远端食管病变引起。口咽性吞咽困难表现为吞咽启动困难、咳嗽、哽噎或吸入,最常见于慢性神经系统疾病,如中风、帕金森病或痴呆。由于存在吸入风险,应彻底评估症状。食管性吞咽困难的患者可能会在吞咽后报告食物卡住的感觉。这种情况最常见于胃食管反流病和功能性食管疾病。嗜酸性食管炎由食物过敏原引发,越来越普遍;应进行食管活检以做出诊断。食管动力障碍,如贲门失弛缓症相对罕见,可能被过度诊断。阿片类药物引起的食管功能障碍越来越常见。推荐对食管性吞咽困难进行食管胃十二指肠镜检查,并用食管钡餐造影作为辅助检查。食管癌和其他严重疾病的患病率较低,在低风险患者中,可能会推迟检测,同时进行四周的抑酸治疗试验。许多患有进行性神经疾病的体弱老年患者存在明显但未被识别的吞咽困难,这大大增加了他们患吸入性肺炎和营养不良的风险。在这些患者中,吞咽困难的诊断应促使在考虑潜在有害干预之前,讨论护理目标。言语病理学家和其他专家与家庭医生合作,可以提供结构化评估,并为安全吞咽、姑息治疗或康复提出适当建议。

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