Moszyński K, Lewelt W
Anaesth Resusc Intensive Ther. 1975 Apr-Jun;3(2):135-40.
An outline of the nature and varieties of hyperventilation is presented together with a discussion on the role of artificial hyperventilation in the management of neurosurgical patients. Attention is called to the value of gasometric investigations in the ventricular cerebrospinal fluid for evaluation of disturbances in pH of the intracranial environment and possible effectiveness of hyperventilation. The results of our measurements of cerebrospinal fluid pressure are presented in 21 cases of supratentorial cerebral tumours in which controlled ventilation with hyperventilation was conducted. In 19 cases, the cerebrospinal fluid pressure fell by a mean of 44.3% with a simultaneous fall of PaCO2 by 29.3%. In the conclusions the authors stress the role of hyperventilation in the lowering of raised cerebrospinal fluid pressure and prevention of cerebral oedema.
本文介绍了过度换气的性质和类型，并讨论了人工过度换气在神经外科患者管理中的作用。文中还提到了通过测定脑室脑脊液气体来评估颅内环境pH值紊乱及过度换气可能疗效的价值。本文给出了对21例幕上脑肿瘤患者进行控制通气及过度换气时脑脊液压力的测量结果。19例患者脑脊液压力平均下降44.3%，同时动脉血二氧化碳分压下降29.3%。作者在结论中强调了过度换气在降低升高的脑脊液压力和预防脑水肿方面的作用。
