• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

慢性肾脏病：CKD 的分类不应仅仅关乎预后。

Chronic kidney disease: classification of CKD should be about more than prognosis.

机构信息

Division of Nephrology and Hypertension and Division of Epidemiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.

出版信息

Nat Rev Nephrol. 2013 Dec;9(12):697-8. doi: 10.1038/nrneph.2013.222. Epub 2013 Oct 15.

DOI:10.1038/nrneph.2013.222
PMID:24126591
Abstract

Cystatin C continues to show its superiority over serum creatinine in predicting mortality among patients with chronic kidney disease (CKD). This superiority is, in part, due to the non-glomerular filtration rate (GFR) determinants of cystatin C associating with CKD risk factors and outcomes. The definition and classification of CKD should not exclusively equate cystatin C with GFR.

摘要

半胱氨酸蛋白酶抑制剂 C 在预测慢性肾脏病 (CKD) 患者死亡率方面继续优于血清肌酐。这种优越性部分归因于半胱氨酸蛋白酶抑制剂 C 的非肾小球滤过率 (GFR) 决定因素与 CKD 危险因素和结局相关。CKD 的定义和分类不应将半胱氨酸蛋白酶抑制剂 C 与 GFR 等同起来。

相似文献

1
Chronic kidney disease: classification of CKD should be about more than prognosis.慢性肾脏病：CKD 的分类不应仅仅关乎预后。
Nat Rev Nephrol. 2013 Dec;9(12):697-8. doi: 10.1038/nrneph.2013.222. Epub 2013 Oct 15.
2
Pretransplant renal function according to CKD-EPI cystatin C equation is a prognostic factor of death after liver transplantation.移植前根据 CKD-EPI 胱抑素 C 方程估算的肾功能是肝移植后死亡的预后因素。
Liver Int. 2016 Apr;36(4):547-54. doi: 10.1111/liv.12989. Epub 2016 Jan 30.
3
Staging chronic kidney disease and estimating glomerular filtration rate: an opinion paper about the new international recommendations.分期慢性肾脏病和估计肾小球滤过率：关于新的国际建议的意见文件。
Clin Chem Lab Med. 2013 Oct;51(10):1911-7. doi: 10.1515/cclm-2013-0223.
4
Age, stage and biomarkers for the definition of CKD: a construction in progress.慢性肾脏病定义的年龄、分期和生物标志物：一项正在进行的构建。
Clin Chem Lab Med. 2013 Oct;51(10):1919-23. doi: 10.1515/cclm-2013-0431.
5
Newer glomerular filtration rate estimating equations for the full age spectrum based on serum creatinine and cystatin C in predicting mortality in patients with ischemic stroke.基于血清肌酐和胱抑素 C 的新型全年龄段肾小球滤过率估算方程在预测缺血性脑卒中患者死亡率中的应用。
Eur J Intern Med. 2018 Jun;52:67-72. doi: 10.1016/j.ejim.2018.02.005. Epub 2018 Feb 9.
6
Cystatin C-calculated Glomerular Filtration Rate-A Marker of Early Renal Dysfunction in Patients With Neuropathic Bladder.胱抑素C计算的肾小球滤过率——神经源性膀胱患者早期肾功能障碍的标志物
Urology. 2017 Feb;100:213-217. doi: 10.1016/j.urology.2016.08.011. Epub 2016 Aug 16.
7
Calibration and precision of serum creatinine and plasma cystatin C measurement: impact on the estimation of glomerular filtration rate.血清肌酐和血浆胱抑素C测量的校准与精密度：对肾小球滤过率估算的影响
J Nephrol. 2014 Oct;27(5):467-75. doi: 10.1007/s40620-014-0087-7. Epub 2014 Apr 8.
8
Comparison of MDRD and the old CKD-EPI equations with the new CKD-EPI equations in kidney transplant patients when glomerular filtration rate is measured with 51Cr-EDTA.比较 MDRD 和旧的 CKD-EPI 方程与新的 CKD-EPI 方程在使用 51Cr-EDTA 测量肾小球滤过率时在肾移植患者中的应用。
Nefrologia (Engl Ed). 2020 Jan-Feb;40(1):53-64. doi: 10.1016/j.nefro.2019.07.006. Epub 2019 Dec 13.
9
Creatinine-or cystatin C-based equations to estimate glomerular filtration in the general population: impact on the epidemiology of chronic kidney disease.基于肌酐或胱抑素 C 的方程估算普通人群肾小球滤过率：对慢性肾脏病流行病学的影响。
BMC Nephrol. 2013 Mar 12;14:57. doi: 10.1186/1471-2369-14-57.
10
Estimation of Glomerular Filtration Rate in Elderly Chronic Kidney Disease Patients: Comparison of Three Novel Sophisticated Equations and Simple Cystatin C Equation.老年慢性肾脏病患者肾小球滤过率的估算：三种新型复杂方程与简单胱抑素C方程的比较
Ther Apher Dial. 2017 Apr;21(2):126-132. doi: 10.1111/1744-9987.12523. Epub 2017 Mar 10.

引用本文的文献

1
CKD: A Call for an Age-Adapted Definition.CKD：呼吁制定适合年龄的定义。
J Am Soc Nephrol. 2019 Oct;30(10):1785-1805. doi: 10.1681/ASN.2019030238. Epub 2019 Sep 10.
2
Assessing the prevalence of chronic kidney disease in the community: Estimating glomerular filtration rate is the Achilles heel.评估社区慢性肾脏病的患病率：估算肾小球滤过率是关键难题。
Indian J Nephrol. 2014 Nov;24(6):411-2.

本文引用的文献

1
Cystatin C versus creatinine in determining risk based on kidney function.胱抑素 C 与肌酐在基于肾功能的风险评估中的比较。
N Engl J Med. 2013 Sep 5;369(10):932-43. doi: 10.1056/NEJMoa1214234.
2
GFR estimating equations: getting closer to the truth?肾小球滤过率估算方程：更接近真相？
Clin J Am Soc Nephrol. 2013 Aug;8(8):1414-20. doi: 10.2215/CJN.01240213. Epub 2013 May 23.
3
Estimating the glomerular filtration rate from serum creatinine is better than from cystatin C for evaluating risk factors associated with chronic kidney disease.
用血清肌酐估算肾小球滤过率比用胱抑素 C 评估与慢性肾脏病相关的危险因素更好。
Kidney Int. 2013 Jun;83(6):1169-76. doi: 10.1038/ki.2013.7. Epub 2013 Feb 20.
4
Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate.比较 CKD-EPI 方程和 MDRD 研究方程用于估计肾小球滤过率的风险预测。
JAMA. 2012 May 9;307(18):1941-51. doi: 10.1001/jama.2012.3954.
5
Cystatin C identifies chronic kidney disease patients at higher risk for complications.胱抑素 C 可识别出发生并发症风险较高的慢性肾脏病患者。
J Am Soc Nephrol. 2011 Jan;22(1):147-55. doi: 10.1681/ASN.2010050483. Epub 2010 Dec 16.
6
Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: modulation by interferon-β and role played in cell migration.组织蛋白酶（S 和 B）及其抑制剂胱抑素 C 在免疫细胞中的作用：干扰素-β的调节及其在细胞迁移中的作用。
J Neuroimmunol. 2011 Mar;232(1-2):200-6. doi: 10.1016/j.jneuroim.2010.10.015. Epub 2010 Nov 26.
7
Cathepsins and cystatin C in atherosclerosis and obesity.组织蛋白酶和胱抑素 C 在动脉粥样硬化和肥胖中的作用。
Biochimie. 2010 Nov;92(11):1580-6. doi: 10.1016/j.biochi.2010.04.011. Epub 2010 Apr 24.
8
Definition and classification of CKD: the debate should be about patient prognosis--a position statement from KDOQI and KDIGO.慢性肾脏病的定义与分类：争论应聚焦于患者预后——来自美国肾脏病预后质量倡议组织（KDOQI）和改善全球肾脏病预后组织（KDIGO）的立场声明
Am J Kidney Dis. 2009 Jun;53(6):915-20. doi: 10.1053/j.ajkd.2009.04.001. Epub 2009 May 5.
9
K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.《肾脏病生存质量指导（K/DOQI）慢性肾脏病临床实践指南：评估、分类及分层》
Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-266.