Riesterer Oliver
Klinik und Poliklinik für Radio-Onkologie, Universitätsspital Zürich.
Praxis (Bern 1994). 2013 Oct 16;102(21):1309-16. doi: 10.1024/1661-8157/a001440.
Stereotactic body radiotherapy (SBRT) is a new radiation technique that combines improvements in radiotherapy planning, intensity modulation and image guidance. The use of SBRT enables radiotherapy to be delivered instead of in six weeks in only a few days and with ablative total dose. Prospective phase II studies in patients with inoperable early stage non-small cell lung cancer demonstrate that the use of SBRT results in local control rates of 85-95% with acceptable toxicity. SBRT is also increasingly used for treatment of metastases in the lung, liver, retroperitoneum and in bones. Because SBRT enables a locally curative dose to be delivered in a time efficient manner this technique also opens up new perspectives for the treatment of patients with oligometastases.
立体定向体部放疗(SBRT)是一种新的放疗技术,它结合了放疗计划、调强放疗和图像引导方面的改进。使用SBRT可使放疗在短短几天内完成,而不是六周时间,并且给予消融性总剂量。对无法手术的早期非小细胞肺癌患者进行的前瞻性II期研究表明,使用SBRT可使局部控制率达到85%-95%,且毒性可接受。SBRT也越来越多地用于治疗肺、肝、腹膜后和骨骼的转移瘤。由于SBRT能够以高效的方式给予局部治愈剂量,该技术也为寡转移患者的治疗开辟了新的前景。