Ito M
Infect Immun. 1985 Oct;50(1):333-5. doi: 10.1128/iai.50.1.333-335.1985.
The local Shwartzman reaction occurred in germfree rabbits which had no natural antibody to endotoxin and none or only a very small amount of immunoglobulin G. From the results it was concluded that the presence of natural antibody to endotoxin is not a prerequisite of the production of the local Shwartzman reaction by bacterial endotoxin.