Weisburg W G, Oyaizu Y, Oyaizu H, Woese C R
J Bacteriol. 1985 Oct;164(1):230-6. doi: 10.1128/jb.164.1.230-236.1985.
Comparisons among 16S rRNA sequences from various eubacteria reveal a natural relationship between the bacteroides (represented by the Bacteroides fragilis sequence) and a phylogenetic unit that comprises the flavobacteria, cytophagae, flexibacteria, and others (represented by the Flavobacterium heparinum sequence). Although the relationship is not a close one, it is, nevertheless, specific. rRNAs from these two organisms are not only closer to one another in overall sequence than they are to outgroup species (such as Bacillus subtilis, Escherichia coli, Desulfovibrio desulfuricans, and Agrobacterium tumefaciens), but they show common idiosyncrasies (i.e., derived characteristics) in both rRNA sequences and higher-order structures.
对各种真细菌的16S rRNA序列进行比较后发现,拟杆菌(以脆弱拟杆菌序列为代表)与一个系统发育单元之间存在天然联系,该系统发育单元包括黄杆菌、噬细胞菌、屈挠杆菌等(以肝素黄杆菌序列为代表)。尽管这种关系并不紧密,但却是特定的。这两种生物的rRNA不仅在总体序列上彼此比与外群物种(如枯草芽孢杆菌、大肠杆菌、脱硫脱硫弧菌和根癌土壤杆菌)更接近,而且在rRNA序列和高级结构上都表现出共同的特质(即衍生特征)。