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1
Membrane phenotypic studies in B cell lymphoproliferative disorders.B细胞淋巴增殖性疾病的膜表型研究。
J Clin Pathol. 1985 Sep;38(9):995-1001. doi: 10.1136/jcp.38.9.995.
2
Prolymphocytoid variants of chronic lymphocytic leukaemia: an immunological and morphological survey.慢性淋巴细胞白血病的原淋巴细胞样变异型：一项免疫学和形态学研究
Leuk Res. 1987;11(2):135-40. doi: 10.1016/0145-2126(87)90018-x.
3
Chronic lymphocytic leukaemia cells activated in vitro reveal cellular changes that characterize B-prolymphocytic leukaemia and immunocytoma.
Scand J Immunol. 1983 May;17(5):397-401. doi: 10.1111/j.1365-3083.1983.tb00805.x.
4
Incidence of phenotypic aberrations in a series of 467 patients with B chronic lymphoproliferative disorders: basis for the design of specific four-color stainings to be used for minimal residual disease investigation.467例B细胞慢性淋巴细胞增殖性疾病患者的表型异常发生率：用于微小残留病研究的特定四色染色设计基础
Leukemia. 2002 Aug;16(8):1460-9. doi: 10.1038/sj.leu.2402584.
5
Expression and modulation of common acute lymphoblastic leukaemia antigen by B prolymphocytic leukaemia cells.B 前淋巴细胞白血病细胞对常见急性淋巴细胞白血病抗原的表达与调控
Immunol Lett. 1985;9(5):263-6. doi: 10.1016/0165-2478(85)90005-7.
6
[2 phenotypic variants of B-cell lymphocytic leukemia].B 细胞淋巴细胞白血病的 2 种表型变体
Eksp Onkol. 1988;10(1):40-3.
7
Detection of the common acute lymphoblastic leukaemia antigen (CALLA) on B cells from human fetal tissues. A multiple phenotypic characterization.人胎儿组织B细胞上常见急性淋巴细胞白血病抗原（CALLA）的检测。多重表型特征分析。
Clin Exp Immunol. 1985 Feb;59(2):305-14.
8
Prolymphocytoid transformation of CLL: a clinical and immunological study of 22 cases.
Leuk Res. 1986;10(10):1225-32. doi: 10.1016/0145-2126(86)90241-9.
9
Expression of the T1 (CD5, p67) surface antigen in B-CLL and B-NHL and its correlation with other B-cell differentiation markers.T1（CD5，p67）表面抗原在B细胞慢性淋巴细胞白血病和B细胞非霍奇金淋巴瘤中的表达及其与其他B细胞分化标志物的相关性。
Hematol Oncol. 1986 Jul-Sep;4(3):237-48. doi: 10.1002/hon.2900040308.
10
Current concepts in immunology: Cell-surface markers in lymphoproliferative disease.免疫学的当前概念：淋巴增生性疾病中的细胞表面标志物
N Engl J Med. 1981 Feb 5;304(6):331-6. doi: 10.1056/NEJM198102053040606.

引用本文的文献

1
What Does Atypical Chronic Lymphocytic Leukemia Really Mean? A Retrospective Morphological and Immunophenotypic Study.非典型慢性淋巴细胞白血病究竟意味着什么？一项回顾性形态学和免疫表型研究。
Cancers (Basel). 2024 Jan 22;16(2):469. doi: 10.3390/cancers16020469.
2
Proposed relation between expression of interleukin-2 and transferrin receptors in B lymphocyte chronic lymphocytic leukaemia.B淋巴细胞慢性淋巴细胞白血病中白细胞介素-2表达与转铁蛋白受体之间的拟议关系。
J Clin Pathol. 1987 Jul;40(7):814. doi: 10.1136/jcp.40.7.814.
3
Cell surface expression of beta 2-microglobulin (beta 2m) correlates with stages of differentiation in B cell tumours.β2微球蛋白（β2m）的细胞表面表达与B细胞肿瘤的分化阶段相关。
J Clin Pathol. 1987 May;40(5):486-9. doi: 10.1136/jcp.40.5.486.
4
Morphological and immunological changes of hairy cell leukemia during alpha-2-interferon therapy.α-2干扰素治疗期间毛细胞白血病的形态学和免疫学变化
Blut. 1989 May;58(5):261-4. doi: 10.1007/BF00320916.

本文引用的文献

1
Prolymphocytic transformation of chronic lymphocytic leukemia.
Cancer. 1981 Dec 1;48(11):2447-57. doi: 10.1002/1097-0142(19811201)48:11<2447::aid-cncr2820481118>3.0.co;2-b.
2
Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin.由单克隆抗体定义的人类T细胞抗原：T细胞的65000道尔顿抗原（T65）也存在于带有表面免疫球蛋白的慢性淋巴细胞白血病细胞上。
J Immunol. 1980 Aug;125(2):725-31.
3
Expression of common acute lymphoblastic leukemia antigen (CALLA) by lymphomas of B-cell and T-cell lineage.B细胞和T细胞系淋巴瘤中常见急性淋巴细胞白血病抗原（CALLA）的表达。
Blood. 1981 Sep;58(3):648-52.
4
Human lymphocyte markers defined by antibodies derived from somatic cell hybrids. IV. A monoclonal antibody reacting specifically with a subpopulation of human B lymphocytes.由体细胞杂交产生的抗体所界定的人类淋巴细胞标志物。IV. 一种与人类B淋巴细胞亚群特异性反应的单克隆抗体。
J Immunol. 1981 Apr;126(4):1373-7.
5
An antigen shared by a human T cell subset and B cell chronic lymphocytic leukemic cells. Distribution on normal and malignant lymphoid cells.一种人类T细胞亚群与B细胞慢性淋巴细胞白血病细胞共有的抗原。在正常和恶性淋巴细胞上的分布。
J Exp Med. 1980 Jul 1;152(1):229-34. doi: 10.1084/jem.152.1.229.
6
Heterogeneity of B-cell leukemias demonstrated by the monoclonal antibody FMC7.单克隆抗体FMC7所显示的B细胞白血病的异质性。
Blood. 1981 Aug;58(2):406-8.
7
Clinical patterns in B lymphoid malignancy.B淋巴细胞恶性肿瘤的临床模式
Clin Haematol. 1982 Oct;11(3):561-87.
8
The normal and malignant germinal centre.正常和恶性生发中心。
Clin Haematol. 1982 Oct;11(3):531-59.
9
Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation.人类B细胞相关抗原在白血病和淋巴瘤中的表达：一种人类B细胞分化模型
Blood. 1984 Jun;63(6):1424-33.
10
Expression of a T-cell antigen (Leu-1) by B-cell lymphomas.B细胞淋巴瘤中T细胞抗原（Leu-1）的表达。
Am J Pathol. 1983 Nov;113(2):165-71.

B细胞淋巴增殖性疾病的膜表型研究。

Membrane phenotypic studies in B cell lymphoproliferative disorders.

作者信息

Scott C S, Limbert H J, MacKarill I D, Roberts B E

出版信息

J Clin Pathol. 1985 Sep;38(9):995-1001. doi: 10.1136/jcp.38.9.995.

DOI:10.1136/jcp.38.9.995
PMID:2413082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC499348/
Abstract

A total of 398 cases of B cell lymphoproliferative disease were phenotypically characterised by membrane mouse red blood cell (MRBC) receptor, surface immunoglobulin, common acute lymphoblastic leukaemia (CALLA), and FMC7 and T1 monoclonal antibody studies. Relations between chronic lymphocytic leukaemia (CLL), prolymphocytic leukaemia (PLL), and "prolymphocytoid" CLL variants were examined with particular reference to the expression of FMC7. In addition, the reactivity of TU1 monoclonal antibody with B cell disorders was established. The results suggest that despite some heterogeneity most cases may be characterised by their phenotypic patterns and that these investigations provide a reproducible basis for classification.

摘要

总共398例B细胞淋巴增殖性疾病通过膜小鼠红细胞（MRBC）受体、表面免疫球蛋白、普通急性淋巴细胞白血病（CALLA）以及FMC7和T1单克隆抗体研究进行了表型特征分析。对慢性淋巴细胞白血病（CLL）、幼淋巴细胞白血病（PLL）和“幼淋巴细胞样”CLL变体之间的关系进行了研究，特别参考了FMC7的表达。此外，确定了TU1单克隆抗体与B细胞疾病的反应性。结果表明，尽管存在一些异质性，但大多数病例可以通过其表型模式来表征，并且这些研究为分类提供了可重复的基础。