Kivistö K, Alapulli H, Tupola S, Alaluusua S, Kivitie-Kallio S
Department of Social Pediatrics, Hospital for Children and Adolescents, Helsinki University Central Hospital, University of Helsinki, P.O. Box 280, 00029 HUS, Helsinki, Finland,
Eur Arch Paediatr Dent. 2014 Jun;15(3):197-202. doi: 10.1007/s40368-013-0095-7. Epub 2013 Oct 17.
To study the oral health and dental neglect of prenatally buprenorphine-exposed 3-year-old children.
The study consisted of 51 children who as newborns tested positive for buprenorphine in a urine screen. The control group comprised 68 children previously unexposed to narcotics. The dentist examined the children and interviewed their guardians.
Buprenorphine-exposed children exhibited significantly more early childhood caries than did the control group. Caries indices, the number of decayed, missing and filled teeth or tooth surfaces and decayed teeth were greater in the buprenorphine-exposed children than the control children (p = 0.004, p = 0.004, p = 0.001, respectively). In the buprenorphine group, more children showed visible plaque (p = 0.003) and fewer children were caries-free (p = 0.009) than in the control group. The control children's teeth were also brushed more often than the buprenorphine-exposed children's teeth (p = 0.001) and the parents were more involved in their children's tooth brushing than were those in the buprenorphine-exposed group (p = 0.035).
More caries and dental neglect were found in buprenorphine-exposed children than in controls. These findings highlight the importance of routine dental appointments, caries screening and preventive care for children in substance-abusing families.
研究产前暴露于丁丙诺啡的3岁儿童的口腔健康状况及牙齿保健忽视情况。
该研究纳入了51名新生儿尿液筛查丁丙诺啡呈阳性的儿童。对照组由68名既往未接触过麻醉药品的儿童组成。牙医对这些儿童进行了检查并与其监护人进行了访谈。
暴露于丁丙诺啡的儿童比对照组儿童表现出更多的幼儿龋齿。暴露于丁丙诺啡的儿童的龋病指数、龋失补牙或牙面数以及龋坏牙齿数均高于对照组儿童(分别为p = 0.004、p = 0.004、p = 0.001)。与对照组相比,丁丙诺啡组有更多儿童出现可见牙菌斑(p = 0.003),且无龋儿童更少(p = 0.009)。对照组儿童刷牙频率也高于暴露于丁丙诺啡的儿童(p = 0.001),且其父母比暴露于丁丙诺啡组的父母更积极参与孩子的刷牙过程(p = 0.035)。
与对照组相比,暴露于丁丙诺啡的儿童有更多龋齿且牙齿保健被忽视情况更严重。这些发现凸显了对药物滥用家庭中的儿童进行定期牙科检查、龋病筛查和预防性护理的重要性。