一名两岁女童的化疗相关性雷诺现象。

Chemotherapy-associated Raynaud's phenomenon in a two-year-old girl.

作者信息

McGuire W A, Passo M H, Weetman R M

出版信息

Med Pediatr Oncol. 1985;13(6):392-4. doi: 10.1002/mpo.2950130619.

Abstract

Raynaud's phenomenon occurred in a 2-year-old girl 17 months after starting multiagent chemotherapy for an endodermal sinus tumor of the vagina. Symptoms began 2 months after receiving her final dose of bleomycin, and gradually resolved over a 6-month period despite continuing vinblastine. Chemotherapy-associated Raynaud's phenomenon appears to be unusual in young children, although mild episodes of vasospasm may not be reported by children or their parents. Specific questions regarding symptoms of Raynaud's phenomenon should be asked of all children receiving vinblastine and bleomycin therapy.

摘要

一名2岁女童在开始针对阴道内胚窦瘤进行多药化疗17个月后出现雷诺现象。症状在接受最后一剂博来霉素2个月后开始出现，尽管继续使用长春新碱，但在6个月内逐渐缓解。化疗相关的雷诺现象在幼儿中似乎不常见，尽管儿童或其父母可能未报告轻度血管痉挛发作。对于所有接受长春新碱和博来霉素治疗的儿童，都应询问有关雷诺现象症状的具体问题。