DSM-5 与 RDoC：精神病学研究的进展？
DSM-5 and RDoC: progress in psychiatry research?
机构信息
Sackler Institute for Developmental Psychobiology, Department of Psychiatry, Weill Medical College of Cornell University, New York, New York 10065, USA.
出版信息
Nat Rev Neurosci. 2013 Nov;14(11):810-4. doi: 10.1038/nrn3621.
Neuroscience studies into psychiatric disorders generally rely on disease definitions that are based on the influential Diagnostic and Statistical Manual of Mental Disorders (DSM), the fifth edition of which (DSM-5) was released earlier this year. Designed as a purely diagnostic tool, the DSM considers different disorders as distinct entities. However, boundaries between disorders are often not as strict as the DSM suggests. To provide an alternative framework for research into psychiatric disorders, the US National Institute of Mental Health (NIMH) has recently introduced its Research Domain Criteria (RDoC) project. In the RDoC, five 'domains' each reflect a brain system in which functioning is impaired, to different degrees, in different psychiatric conditions. Nature Reviews Neuroscience asked six leading investigators for their thoughts on how DSM-5 and the RDoC will influence neuroscience research into psychiatric disorders.
神经科学对精神障碍的研究通常依赖于基于有影响力的《精神疾病诊断与统计手册》（DSM）的疾病定义，其第五版（DSM-5）于今年早些时候发布。作为一种纯粹的诊断工具，DSM 将不同的障碍视为不同的实体。然而，障碍之间的界限并不像 DSM 所暗示的那样严格。为了提供一个替代的框架来研究精神障碍，美国国家心理健康研究所（NIMH）最近推出了其研究领域标准（RDoC）项目。在 RDoC 中，五个“领域”分别反映了大脑系统，在不同的精神障碍中，不同程度地受到功能障碍的影响。《自然综述：神经科学》就 DSM-5 和 RDoC 将如何影响神经科学对精神障碍的研究，向六位主要研究人员征求了意见。
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