高载药纳米粒的形状设计，以实现更有效的癌症治疗。
Shape design of high drug payload nanoparticles for more effective cancer therapy.
机构信息
Functional Nano & Soft Materials Laboratory (FUNSOM) and Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu 215123, China.
出版信息
Chem Commun (Camb). 2013 Dec 4;49(93):10989-91. doi: 10.1039/c3cc46718j.
PMID:24136236
Abstract
We developed different-shaped drug nanocrystals with similar hydrodynamic sizes and surface charges, and found that nanorods exhibited much higher in vitro and in vivo anticancer efficacy than that of nanospheres.
摘要
我们制备了具有相似水动力粒径和表面电荷的不同形貌的药物纳米晶，发现纳米棒的体外和体内抗肿瘤疗效明显优于纳米球。
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