[氯化钙对干扰素形成诱导的调节作用]
[Modulation of the induction of interferon formation by calcium chloride].
作者信息
Orlova T G, Bokhon'ko A I, Mamontova T V, Kognovitskaia A I
出版信息
Vopr Virusol. 1985 May-Jun;30(3):347-50.
PMID:2413629
Abstract
The results of the study confirm earlier reports on the stimulating effect of calcium ions on production of interferon induced by poly(I) X poly(C) and on translation of messenger RNA for interferon. Neutralization of the inhibiting activity of interferon production suppressor present in the cytoplasm of normal cells has first been demonstrated which broadens our concepts on the mechanism of action of calcium ions.
摘要
该研究结果证实了早期有关钙离子对聚肌苷酸×聚胞苷酸诱导的干扰素产生的刺激作用以及对干扰素信使核糖核酸翻译的报道。首次证明了对正常细胞胞质中存在的干扰素产生抑制剂的抑制活性的中和作用，这拓宽了我们对钙离子作用机制的认识。
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