[小鼠细胞产生低反应性因子]
[Production of the hyporeactivity factor by mouse cells].
作者信息
Sokolova T M, Gevorkian M G, Ershov F I
出版信息
Biull Eksp Biol Med. 1984 Sep;98(9):329-30.
PMID:6207869
Abstract
The mouse cells L 929 experiencing the state of hyporeactivity to repeated interferon induction with the aid of poly (I) X poly (C) secrete to the incubation medium a factor which suppresses interferon production. The factor is not neutralized by antiserum against murine interferon. Apart from hyporeactivity factor, interferon itself may inhibit its own production.
摘要
借助聚肌苷酸×聚胞苷酸对小鼠L929细胞进行反复干扰素诱导时，处于低反应性状态的这些细胞会向培养液中分泌一种抑制干扰素产生的因子。该因子不能被抗鼠干扰素的抗血清中和。除低反应性因子外，干扰素自身也可能抑制其自身的产生。
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