过度使用鼻喷雾剂后发生视网膜分支动脉阻塞。
Branch retinal artery occlusion after excessive use of nasal spray.
作者信息
Magargal L E, Sanborn G E, Donoso L A, Gonder J R
出版信息
Ann Ophthalmol. 1985 Aug;17(8):500-1.
PMID:2413795
Abstract
A young, otherwise healthy man presented with an acute retinal artery obstruction following excessive use of oxymethazolone hydrochloride 0.5% (Afrin) nasal spray. Platelet coagulation studies indicated a platelet aggregation hypersensitivity to adenosine diphosphate and epinephrine. A predisposition for sympathomimetic drug-induced platelet fibrin embolus formation appears to be the cause of the retinal artery obstruction in this case.
摘要
一名年轻且其他方面健康的男性，在过量使用0.5%盐酸羟甲唑啉（阿弗林）鼻喷雾剂后出现急性视网膜动脉阻塞。血小板凝血研究表明血小板对二磷酸腺苷和肾上腺素的聚集超敏。在这种情况下，拟交感神经药物诱导的血小板纤维蛋白栓子形成倾向似乎是视网膜动脉阻塞的原因。
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