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Ischemic Stroke Associated with Chronic Xylometazoline Nasal Spray Misuse: A Rare Avoidable Adverse Event.

作者信息

Patel Jalpan, Patel Ishani, Desai Devangi, Desai Soaham

机构信息

Physician Doctor, Shree Krishna Hospital, Pramukhswami Medical College, Karamsad, Anand, Gujarat, India.

Professor in Medicine Department, Shree Krishna Hospital, Pramukhswami Medical College, Karamsad, Anand, Gujarat, India.

出版信息

Ann Indian Acad Neurol. 2021 Mar-Apr;24(2):304-307. doi: 10.4103/aian.AIAN_291_20. Epub 2020 Jul 8.

DOI:10.4103/aian.AIAN_291_20
PMID:34220102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8232514/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe47/8232514/64aa0dbed235/AIAN-24-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe47/8232514/e7c6ef7856d6/AIAN-24-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe47/8232514/64aa0dbed235/AIAN-24-304-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe47/8232514/e7c6ef7856d6/AIAN-24-304-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe47/8232514/64aa0dbed235/AIAN-24-304-g002.jpg

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ArXiv. 2025 Apr 22:arXiv:2505.04631v1.

本文引用的文献

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Reversible cerebral vasoconstriction syndrome presenting as an isolated primary intraventricular hemorrhage.表现为孤立性原发性脑室内出血的可逆性脑血管收缩综合征
Chin Neurosurg J. 2018 Jun 4;4:11. doi: 10.1186/s41016-018-0118-7. eCollection 2018.
2
Myocardial infarction and ischemic stroke with vasoconstrictors used as nasal decongestant for common cold: a French pharmacovigilance survey.将血管收缩剂用作普通感冒的鼻减充血剂引发心肌梗死和缺血性中风：一项法国药物警戒调查。
Eur J Clin Pharmacol. 2020 Apr;76(4):603-604. doi: 10.1007/s00228-019-02807-w. Epub 2019 Dec 20.
3
Systemic side effects of locally used oxymetazoline.
局部使用羟甲唑啉的全身副作用。
Int J Clin Exp Med. 2015 Feb 15;8(2):2674-8. eCollection 2015.
4
Bilateral thalamic stroke due to nasal ephedrine and naphazoline use.因使用鼻用麻黄碱和萘甲唑啉导致的双侧丘脑中风。
Neurol Sci. 2015 Jul;36(7):1285-6. doi: 10.1007/s10072-014-2030-z. Epub 2014 Dec 20.
5
Xylometazoline abuse induced ischemic stroke in a young adult.赛洛唑啉滥用导致一名年轻成年人发生缺血性中风。
Neurologist. 2011 Jan;17(1):41-3. doi: 10.1097/NRL.0b013e3181d2ab04.
6
Ischemic stroke in a man with naphazoline abuse history.一名有萘甲唑啉滥用史的男性发生缺血性中风。
Am J Emerg Med. 2007 Oct;25(8):983.e1-2. doi: 10.1016/j.ajem.2007.02.018.
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Hemorrhagic stroke after naphazoline exposition: case report.使用萘甲唑啉后发生出血性中风：病例报告。
Arq Neuropsiquiatr. 2004 Sep;62(3B):889-91. doi: 10.1590/s0004-282x2004000500030. Epub 2004 Oct 5.
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Stroke associated with sympathomimetics contained in over-the-counter cough and cold drugs.与非处方止咳和感冒药中含有的拟交感神经药相关的中风。
Stroke. 2003 Jul;34(7):1667-72. doi: 10.1161/01.STR.0000075293.45936.FA. Epub 2003 Jun 5.
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Phenylpropanolamine and the risk of hemorrhagic stroke.苯丙醇胺与出血性中风风险
N Engl J Med. 2000 Dec 21;343(25):1826-32. doi: 10.1056/NEJM200012213432501.
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The distribution of adrenergic receptors in cerebral blood vessels: an autoradiographic study.脑血管中肾上腺素能受体的分布：一项放射自显影研究。
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