Dionisi O, Galeotti T, Terranova T, Azzi A
Biochim Biophys Acta. 1975 Oct 22;403(2):292-300. doi: 10.1016/0005-2744(75)90059-5.
Mitochondria from beef heart, Morris hepatoma 3924A and Ehrlich ascites tumor (Lettré mutant) have been studied with respect to hydrogen peroxidase and superoxide radical formation and the presence of superoxide dismutase activity (EC 1.15.1.1, superoxide:superoxide oxidoreductase). The generation of superoxide radicals and hydrogen peroxide occurs at the level of the membrane, being present also in mitochondrial fragments. Hepatoma and ascites mitochondria have little or no superoxide dismutase activity. Superoxide radicals appear to be precursors of hydrogen peroxide formation, the reaction being catalyzed by superoxide dismutase.
已对来自牛心、莫里斯肝癌3924A和艾氏腹水瘤（莱特雷突变体）的线粒体进行了研究，涉及过氧化氢酶和超氧自由基的形成以及超氧化物歧化酶活性（EC 1.15.1.1，超氧化物：超氧化物氧化还原酶）的存在情况。超氧自由基和过氧化氢的生成发生在膜水平，线粒体片段中也存在。肝癌和腹水线粒体的超氧化物歧化酶活性很低或没有。超氧自由基似乎是过氧化氢形成的前体，该反应由超氧化物歧化酶催化。
