Kapadia Bhaveen H, McElroy Mark J, Issa Kimona, Johnson Aaron J, Bozic Kevin J, Mont Michael A
Rubin Institute for Advanced Orthopedics Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, California.
J Arthroplasty. 2014 May;29(5):929-32. doi: 10.1016/j.arth.2013.09.017. Epub 2013 Oct 18.
The purpose of this study was to measure the impact of periprosthetic joint infections (PJIs) on the length of hospitalization, readmissions, and the associated costs. Between 2007 and 2011, our prospectively collected infection database was reviewed to identify PJIs that occurred following primary total knee arthroplasty (TKA), which required a two-stage revision. We identified 21 consecutive patients and matched them to 21 non-infected patients who underwent uncomplicated primary TKA. The patients who had PJIs had significantly longer hospitalizations (5.3 vs. 3.0 days), more readmissions (3.6 vs. 0.1), and more clinic visits (6.5 vs. 1.3) when compared to the matched group, respectively. The mean annual cost was significantly higher in the infected cohort ($116,383; range, $44,416 to $269,914) when compared to the matched group ($28,249; range, $20,454 to $47,957). Periprosthetic infections following TKA represent a tremendous economic burden for tertiary-care centers and to patients.
本研究的目的是评估人工关节周围感染（PJI）对住院时间、再入院情况及相关费用的影响。在2007年至2011年期间，我们回顾了前瞻性收集的感染数据库，以确定初次全膝关节置换术（TKA）后发生的需要二期翻修的PJI。我们确定了21例连续患者，并将他们与21例接受了无并发症初次TKA的未感染患者进行匹配。与匹配组相比，发生PJI的患者住院时间显著更长（5.3天对3.0天）、再入院次数更多（3.6次对0.1次）以及门诊就诊次数更多（6.5次对1.3次）。与匹配组（28,249美元；范围为20,454美元至47,957美元）相比，感染队列的年均费用显著更高（116,383美元；范围为44,416美元至269,914美元）。TKA后的人工关节周围感染对三级护理中心和患者而言是巨大的经济负担。
