Walden J, Witte O W, Speckmann E J
Neurosci Lett. 1985 Sep 30;60(2):139-43. doi: 10.1016/0304-3940(85)90234-4.
In the identified neurons B1, B2 and B3 of Helix pomatia an intracellular injection of Na+ induced an outward current in 10% and an inward current in 90% of the experiments. The outward current was associated with an increase and the inward current with a decrease of the membrane conductance. Both currents reversed at membrane potentials of between -60 and -70 mV. Inward currents were also elicited by intracellular Li+ or tris-[hydroxymethyl]-aminomethane (Tris+) injection. All inward currents were reduced by extracellular administration of tetraethylammonium or quinine. It is suggested that the outward current represents a calcium-activated potassium current and that the inward current is due to a blockade of potassium channels from the intracellular side.
在鉴定出的苹果螺神经元B1、B2和B3中，细胞内注射Na+在10%的实验中诱发外向电流，在90%的实验中诱发内向电流。外向电流与膜电导增加相关，内向电流与膜电导降低相关。两种电流在膜电位-60至-70 mV之间反转。细胞内注射Li+或三（羟甲基）氨基甲烷（Tris+）也可诱发内向电流。所有内向电流都可被细胞外给予四乙铵或奎宁所减弱。提示外向电流代表钙激活钾电流，内向电流是由于从细胞内侧阻断钾通道所致。
