Witte O W, Walden J, Speckmann E J
Brain Res. 1985 Nov 18;347(2):313-20. doi: 10.1016/0006-8993(85)90192-1.
In the identified neurons B1 and B3 of the buccal ganglion of Helix pomatia, the initial acetylcholine (ACh) inward current was succeeded by two types of secondary responses. The secondary responses consisted either in an outward current or in a long-lasting inward current or in a combination of both. The secondary outward current was decreased with membrane hyperpolarization, associated with a decrease of membrane resistance and abolished in Ca2+-free Co2+ solution. It is assumed to be a K+ current activated by an influx of Ca2+. The secondary inward current also decreased with membrane hyperpolarization, but was associated with an increase of the membrane resistance and could be mimicked by an injection of Na+ into the cells. It is suggested to be due to a block of K+ channels by intracellular Na+. When the secondary responses appeared combined, the outward current preceded the inward current.
在鉴定出的苹果螺颊神经节的神经元B1和B3中，最初的乙酰胆碱（ACh）内向电流之后是两种类型的继发性反应。继发性反应要么表现为外向电流，要么表现为持久的内向电流，或者两者兼而有之。继发性外向电流随着膜超极化而减小，与膜电阻降低相关，并在无Ca2+的Co2+溶液中消失。它被认为是由Ca2+内流激活的K+电流。继发性内向电流也随着膜超极化而减小，但与膜电阻增加相关，并且可以通过向细胞内注射Na+来模拟。提示这是由于细胞内Na+阻断了K+通道所致。当继发性反应同时出现时，外向电流先于内向电流出现。
