Suppr超能文献

激光原位角膜磨镶术治疗近视后对干眼症行泪点封闭的疗效。

Efficacy of punctal occlusion in management of dry eyes after laser in situ keratomileusis for myopia.

机构信息

Department of Ophthalmology, College of Medicine, King Saud University , Riyadh , Kingdom of Saudi Arabia .

出版信息

Curr Eye Res. 2014 Mar;39(3):257-62. doi: 10.3109/02713683.2013.841258. Epub 2013 Oct 22.

Abstract

PURPOSE

To evaluate the effect of punctal plug use in preventing dry eye after laser in situ keratomileusis (LASIK).

MATERIALS AND METHODS

A randomized clinical trial at a tertiary eye care center, Riyadh, Saudi Arabia. Participants underwent LASIK for myopia in both eyes and a lower punctal occlusion in one eye only while the other eye served as control. Both eyes received the same postoperative medications except for lubricant duration (subject eye: four times per day for one week; control eye: four times per day for 6 months). Participants were evaluated at 1 week, 2, and 6 months after surgery for signs and symptoms of dry eye. The main outcome measures were visual acuity; ocular surface parameters; and Ocular Surface Disease Index questionnaire.

RESULTS

Seventy-eight eyes of 39 patients were included in this study. The Ocular Surface Disease Index scores of eyes with punctal plugs were better at all follow-up visits, and the differences between both eyes were statistically significant (1 week, p < 0.0001; 2 months, p < 0.0001; 6 months, p = 0.008). At the final follow-up visit, the percentage of normal eyes was higher in eyes with punctal plugs for all ocular surface parameters (Schirmer 1 test, 94.9%; tear breakup time, 77.8%; punctate epithelial keratitis score, 71.8%) compared to eyes without occlusion (Schirmer 1 test, 92.3%; tear breakup time, 58.3%; punctate epithelial keratitis score, 53.8%); however, such differences were not statistically significant.

CONCLUSION

Punctal plug insertion after LASIK surgeries may minimize the need for frequent lubricant application and hence improve patient satisfaction.

摘要

目的

评估 LASIK 术后使用泪点塞预防干眼症的效果。

材料和方法

在沙特阿拉伯利雅得的一家三级眼科中心进行的一项随机临床试验。参与者双眼接受近视 LASIK 手术,仅一只眼行下泪点阻塞,另一只眼作为对照。双眼接受相同的术后药物治疗,但润滑剂使用时间不同(受试眼:术后 1 周每日 4 次,之后每日 4 次,持续 6 个月;对照眼:术后 1 周每日 4 次,之后每日 4 次,持续 6 个月)。术后 1 周、2 个月和 6 个月评估双眼干眼的体征和症状。主要观察指标包括视力、眼表参数和眼表疾病指数(OSDI)问卷。

结果

本研究纳入 39 例患者的 78 只眼。在所有随访中,使用泪点塞的眼 OSDI 评分更好,双眼间差异具有统计学意义(1 周,p<0.0001;2 个月,p<0.0001;6 个月,p=0.008)。在最后一次随访时,使用泪点塞的眼在所有眼表参数中正常眼的比例更高(Schirmer 1 试验:94.9%;泪膜破裂时间:77.8%;点状上皮角膜炎评分:71.8%),而未阻塞的眼分别为(Schirmer 1 试验:92.3%;泪膜破裂时间:58.3%;点状上皮角膜炎评分:53.8%),但差异无统计学意义。

结论

LASIK 术后插入泪点塞可能减少频繁使用润滑剂的需求,从而提高患者满意度。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验