Department of Nutrition, Food and Exercise Sciences, The Florida State University, 120 Convocation Way, Tallahassee, FL, 32306, USA.
Eur J Appl Physiol. 2014 Jan;114(1):105-11. doi: 10.1007/s00421-013-2756-y. Epub 2013 Oct 23.
Impaired leg arterial stiffness (pulse wave velocity, PWV) and vasodilatory function are found after stroke. Acute passive vibration (PV) decreases leg PWV (legPWV) and pressure wave reflection (aortic augmentation index, aAIx) in healthy men. Our objective was to evaluate the effects of acute PV on aAIx and PWV in the paretic and non-paretic sides in stroke survivors.
Eleven stroke survivors (4 females) were randomized to either no-PV (control) or PV (25 Hz and 2 mm amplitude) trials on two separated visits. Following 20 min of supine rest with legs on a vibration platform, blood pressure, PWV, and aAIx were gathered before 10 continuous minutes of control or PV. Measurements were repeated at post-5, post-15, and post-30 min after control or PV.
LegPWV and brachial-ankle PWV (baPWV, systemic stiffness) in paretic and non-paretic sides along with aAIx were significantly (P < 0.05) decreased from baseline at post-5 min after PV compared with control. At post-15 min, paretic and non-paretic legPWV remained significantly lower than baseline, but only non-paretic legPWV was different from control. We noted correlations between changes in paretic legPWV and changes in paretic baPWV (r = 0.47, P = 0.028) and aAIx (r = 0.51, P = 0.017) at post-5 min.
Acute PV applied to the legs of stroke survivors reduces systemic arterial stiffness and aortic wave reflection due to a reduction in leg arterial stiffness, which last longer in the non-paretic than in the paretic leg.
研究发现，中风后腿部动脉僵硬度（脉搏波速度，PWV）和血管舒张功能受损。急性被动振动（PV）可降低健康男性的腿部 PWV（腿部 PWV）和压力波反射（主动脉增强指数，aAIx）。我们的目的是评估急性 PV 对中风幸存者患侧和非患侧的 aAIx 和 PWV 的影响。
11 名中风幸存者（4 名女性）被随机分配到无 PV（对照）或 PV（25 Hz 和 2 毫米振幅）试验，在两次单独的访问中进行。在振动平台上仰卧休息 20 分钟后，在控制或 PV 持续 10 分钟前采集血压、PWV 和 aAIx。在控制或 PV 后 5、15 和 30 分钟重复测量。
与对照相比，患侧和非患侧腿部 PWV 以及臂踝 PWV（系统僵硬度）和 aAIx 在 PV 后 5 分钟时均显著（P <0.05）从基线下降。在 15 分钟时，患侧和非患侧腿部 PWV 仍明显低于基线，但仅非患侧腿部 PWV 与对照不同。我们注意到，在 5 分钟时，患侧腿部 PWV 的变化与患侧臂踝 PWV（r = 0.47，P = 0.028）和 aAIx（r = 0.51，P = 0.017）的变化之间存在相关性。
急性 PV 施加于中风幸存者的腿部可降低腿部动脉僵硬度，从而降低系统动脉僵硬度和主动脉波反射，其在非患侧的持续时间长于患侧。
