Gillenberg A K, Länger F, Brunnemer U, Grünwald V, Krettek C, Gösling T
Unfallchirurgische Klinik, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland,
Orthopade. 2013 Nov;42(11):941-7. doi: 10.1007/s00132-013-2135-8.
The role of percutaneous needle biopsy in the diagnostics of soft tissue tumors is controversially discussed. The specificity of this method has been examined in this study based on the collective of patients treated in our university hospital. Secondly, the influence of the specialization of the treating surgeon has been evaluated.
This study included 96 patients who underwent percutaneous needle biopsy and, if necessary, surgical resection. The specificity, logistic requirements and possible complications of percutaneous biopsy were evaluated. Special attention was paid to the influence of specialization of the treating surgical team on the specificity of the method.
The results of the biopsy were able to define the entity of the lesion correctly in 69.7 %, the dignity in 75.0 % and the grading in 72.0 % of the cases. In the group treated by a specialized team, the specificity of the method was 84.6 % concerning the entity of the lesion, 84.6 % concerning the dignity and 80 % concerning the grading. With regard to the entity the specificity was significantly increased (p < 0.05).
The findings show that percutaneous needle biopsy represents a logistically simple and efficient diagnostic method for soft tissue tumors which is rarely associated with complications. Subsequent treatment should be performed in a specialized centre.
经皮穿刺活检在软组织肿瘤诊断中的作用存在争议。本研究基于我校医院治疗的患者群体，对该方法的特异性进行了检验。其次，评估了主刀医生专业特长的影响。
本研究纳入了96例行经皮穿刺活检且必要时行手术切除的患者。对经皮活检的特异性、后勤保障要求及可能的并发症进行了评估。特别关注了主刀手术团队的专业特长对该方法特异性的影响。
活检结果能够在69.7%的病例中正确界定病变性质，在75.0%的病例中正确界定病变程度，在72.0%的病例中正确界定分级。在由专业团队治疗的组中，该方法对于病变性质的特异性为84.6%，对于病变程度的特异性为84.6%，对于分级的特异性为80%。就病变性质而言，特异性显著提高（p＜0.05）。
研究结果表明，经皮穿刺活检是一种后勤保障简单且高效的软组织肿瘤诊断方法，很少引发并发症。后续治疗应在专业中心进行。
