计算 20 至 40 孕周正常胎儿肺与头之比的新公式。
New formulas for calculating the lung-to-head ratio in healthy fetuses between 20 and 40 weeks' gestation.
机构信息
Department of Obstetrics and Gynecology, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
出版信息
J Ultrasound Med. 2013 Nov;32(11):1939-43. doi: 10.7863/ultra.32.11.1939.
OBJECTIVES
The purpose of this study was to develop new formulas for the expected fetal lung area-to-head circumference ratio in normal singleton pregnancies between 20 and 40 weeks' gestation.
METHODS
The lung-to-head ratio and complete fetal biometric parameters of 126 fetuses between 20 and 40 weeks' gestation were prospectively measured. The lung-to-head ratio was measured by 3 different methods (longest diameter, anteroposterior diameter, and tracing). Formulas for predicting right and left lung-to-head ratios with regard to gestational age and biometric parameters were derived by stepwise regression analysis.
RESULTS
New formulas for calculating right and left lung-to-head ratios by each measurement method were derived. The formulas included gestational age only and no biometric parameters.
CONCLUSIONS
The new formulas for estimating the expected lung-to-head ratio by the 3 different methods in normal singleton pregnancies up to 40 weeks' gestation may help improve the prognostic power of observed-to-expected lung-to-head ratio assessment in fetuses with congenital diaphragmatic hernias.
目的
本研究旨在为 20 至 40 孕周正常单胎妊娠胎儿的预期肺面积与头围比开发新的公式。
方法
前瞻性测量了 126 例 20 至 40 孕周胎儿的肺与头比值和完整胎儿生物测量参数。通过 3 种不同方法（最长直径、前后直径和描记）测量肺与头的比值。通过逐步回归分析得出关于胎龄和生物测量参数的右肺与头比值和左肺与头比值的预测公式。
结果
得出了通过每种测量方法计算右肺与头比值和左肺与头比值的新公式。这些公式仅包含胎龄，不包含任何生物测量参数。
结论
这些新公式可用于估计 3 种不同方法在正常单胎妊娠中直至 40 孕周的预期肺与头比值，有助于提高观察到的与预期肺与头比值评估在先天性膈疝胎儿中的预后能力。
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