Chang Eric Y, Du Jiang, Bae Won C, Statum Sheronda, Chung Christine B
Department of Radiology, VA San Diego Healthcare System, San Diego, California, USA; Department of Radiology, University of California, San Diego Medical Center, San Diego, California, USA.
J Magn Reson Imaging. 2014 Aug;40(2):496-500. doi: 10.1002/jmri.24360. Epub 2013 Oct 23.
To determine if immersion of Achilles tendon segments into various solutions improved qualitative delineation of tendon and affected quantitative MR values of T2 and T2*.
Six Achilles tendons were dissected, sectioned (proximal, midportion, and distal tensile pieces) and imaged at 3T both at baseline in air and after immersion into saline, Fomblin, and perfluorooctyl bromide (PFOB), respectively, for 24 h. Blinded readers qualitatively assessed the delineation of tendon boundaries and quantitatively Carr-Purcell-Meiboom-Gill (CPMG) T2 and ultrashort echo time (UTE) T2* was calculated. Comparison between images obtained in air and in solution was made.
On qualitative evaluation, all images obtained in air had larger air-tissue susceptibility effects. Mean T2 values of saline, Fomblin, and PFOB groups were 16.1 ± 3.7, 16.6 ± 2.9, and 18.8 ± 2.6 ms at baseline in air, and 14.8 ± 4.6, 15.9 ± 3.0, and 17.7 ± 3.0 ms after immersion in the fluid, respectively. Mean T2* values of saline, Fomblin, and PFOB groups were 2.0 ± 0.8, 1.6 ± 0.5, and 1.5 ± 0.5 ms at baseline in air, and 2.1 ± 0.5, 1.6 ± 0.5, and 1.4 ± 0.5 ms after immersion in the fluid, respectively. There was no significant effect of immersion or fluid type on measured T2 or T2* (P > 0.1).
These results validate the continued use of these solutions to prevent tendon specimen dehydration and to minimize susceptibility effects.
确定将跟腱段浸入各种溶液中是否能改善肌腱的定性描绘，并影响T2和T2*的定量磁共振值。
解剖6条跟腱，进行切片（近端、中段和远端拉伸段），并分别在空气中基线状态下以及浸入生理盐水、氟油和全氟辛基溴（PFOB）中24小时后，于3T场强下成像。不知情的读者对肌腱边界的描绘进行定性评估，并计算Carr-Purcell-Meiboom-Gill（CPMG）T2和超短回波时间（UTE）T2*的定量值。对在空气中和溶液中获得的图像进行比较。
在定性评估中，所有在空气中获得的图像具有更大的空气-组织磁化率效应。生理盐水、氟油和PFOB组在空气中基线状态下的平均T2值分别为16.1±3.7、16.6±2.9和18.8±2.6毫秒，浸入液体后分别为14.8±4.6、15.9±3.0和17.7±3.0毫秒。生理盐水、氟油和PFOB组在空气中基线状态下的平均T2值分别为2.0±0.8、1.6±0.5和1.5±0.5毫秒，浸入液体后分别为2.1±0.5、1.6±0.5和1.4±0.5毫秒。浸入或液体类型对测量的T2或T2没有显著影响（P>0.1）。
这些结果证实了继续使用这些溶液来防止肌腱标本脱水并使磁化率效应最小化的做法。
