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立体定向体部放疗治疗早期肺癌。

Stereotactic body radiotherapy for early stage lung cancer.

机构信息

Department of Radiation Oncology, Hiroshima University, Hiroshima, Japan.

出版信息

Cancer Res Treat. 2013 Sep;45(3):155-61. doi: 10.4143/crt.2013.45.3.155. Epub 2013 Sep 30.

DOI:10.4143/crt.2013.45.3.155
PMID:24155673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3804726/
Abstract

Stereotactic body radiation therapy (SBRT) is a newly developed technique currently in clinical use. SBRT originated from stereotactic radiosurgery for intracranial tumors. SBRT has been widely used clinically for lung cancer. The practice of SBRT demands different kinds of patient fixation, breathing control, target determination, treatment planning, and verifications. The history and current standard technique are reviewed. Clinical studies of lung cancer showed high local control rates with acceptable toxicities. Past and on-going clinical trials are reviewed.

摘要

立体定向体部放射治疗（SBRT）是一种新开发的技术，目前已在临床应用。SBRT 起源于颅内肿瘤的立体定向放射外科。SBRT 已广泛应用于肺癌的临床治疗。SBRT 的实施需要各种患者固定、呼吸控制、靶区确定、治疗计划和验证。本文回顾了其历史和当前的标准技术。肺癌的临床研究显示，该技术具有较高的局部控制率和可接受的毒性。本文还对过去和正在进行的临床试验进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/3804726/ed5b1f8d3f7d/crt-45-155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/3804726/ed5b1f8d3f7d/crt-45-155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/989a/3804726/ed5b1f8d3f7d/crt-45-155-g001.jpg

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Stereotactic radiotherapy of primary lung cancer and other targets: results of consultant meeting of the International Atomic Energy Agency.立体定向放疗原发性肺癌及其他病灶：国际原子能机构顾问会议结果。
Int J Radiat Oncol Biol Phys. 2011 Mar 1;79(3):660-9. doi: 10.1016/j.ijrobp.2010.10.004.
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Stereotactic body radiation therapy for inoperable early stage lung cancer.
立体定向体部放射治疗和立体定向放射外科的放射生物学机制。
Radiat Oncol J. 2015 Dec;33(4):265-75. doi: 10.3857/roj.2015.33.4.265. Epub 2015 Dec 30.
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J Radiat Res. 2015 Nov;56(6):904-11. doi: 10.1093/jrr/rrv049. Epub 2015 Sep 2.
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Int J Radiat Oncol Biol Phys. 2015 Sep 1;93(1):166-72. doi: 10.1016/j.ijrobp.2015.05.016. Epub 2015 May 16.
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Int J Clin Oncol. 2014 Aug;19(4):570-8. doi: 10.1007/s10147-014-0717-z. Epub 2014 Jul 5.
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