Takeda Atsuya, Enomoto Tatsuji, Sanuki Naoko, Nakajima Takeshi, Takeda Toshiaki, Sayama Koichi, Kunieda Etsuo
Department of Radiology, Ofuna Chuo Hospital, Kamakura, Japan.
Radiat Med. 2008 Oct;26(8):504-7. doi: 10.1007/s11604-008-0261-8. Epub 2008 Oct 31.
Hypofractionated stereotactic body radiotherapy (SBRT) for pulmonary lesions provides a high local control rate, allows completely painless ambulatory treatment, and is not associated with adverse reactions in most cases. Here we report a 70-year-old lung cancer patient with slight focal pulmonary honeycombing in whom subclinical idiopathic pulmonary fibrosis was exacerbated by SBRT. This experience has important implications for the development of selection criteria prior to SBRT for pulmonary lesions. For SBRT candidates with lung tumors, attention must be paid to the presence of co-morbid interstitial pneumonia even if findings are minimal. Such patients must be informed of potential risks, and careful decision-making must take place when SBRT is being considered.
立体定向体部放射治疗（SBRT）用于肺部病变可提供较高的局部控制率，允许完全无痛的门诊治疗，且在大多数情况下无不良反应。在此，我们报告一名70岁的肺癌患者，其肺部有轻微局灶性蜂窝状改变，接受SBRT后亚临床特发性肺纤维化加重。这一经验对制定肺部病变SBRT治疗前的选择标准具有重要意义。对于患有肺部肿瘤的SBRT候选患者，即使发现的病变很轻微，也必须注意是否存在合并的间质性肺炎。必须告知此类患者潜在风险，在考虑进行SBRT时必须谨慎决策。
