Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Cancer Res Treat. 2013 Sep;45(3):239-43. doi: 10.4143/crt.2013.45.3.239. Epub 2013 Sep 30.
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor, with a low-grade malignant potential, occurring predominantly in children and young adults. Association between AFH and other malignancies has been rarely reported. A 27-year-old man who presented with a palpable abdominal mass was diagnosed as having testicular cancer with multiple liver and lung metastases. At 16 months after chemotherapy, a follow-up computed tomographic scan revealed a supraclavicular mass measuring 3 cm in size, which was suspected to be a recurrence. The patient underwent surgical excision, and the mass was pathologically diagnosed as a AFH. The patient has had no local recurrence and no distant metastasis for 12 months after resection. To the best of our knowledge, this is the first case report of AFH as a second tumor in a patient with testicular cancer.
血管肌纤维母细胞瘤（AFH）是一种罕见的软组织肿瘤，具有低度恶性潜能，主要发生在儿童和青年。AFH 与其他恶性肿瘤之间的关联很少有报道。一名 27 岁男性因可触及的腹部肿块就诊，被诊断为睾丸癌伴多发肝和肺转移。化疗后 16 个月，随访 CT 扫描显示锁骨上肿块大小为 3cm，怀疑复发。患者接受了手术切除，肿块病理诊断为 AFH。患者切除后 12 个月无局部复发，无远处转移。据我们所知，这是首例睾丸癌患者第二肿瘤为 AFH 的病例报告。
