West Lorna Marie, Cordina Maria, Cunningham Scott
Mater Dei Hospital. Tal-Qroqq ( Malta ).
Pharm Pract (Granada). 2012 Oct;10(4):181-7. doi: 10.4321/s1886-36552012000400001. Epub 2012 Dec 31.
Appropriate prescribing remains an important priority in all medical areas of practice.
The objective of this study was to apply a Medication Appropriateness Index (MAI) to identify issues of inappropriate prescribing amongst patients admitted from the Emergency Department (ED).
This study was carried out at Malta's general hospital on 125 patients following a two-week pilot period on 10 patients. Patients aged 18 years and over and on medication therapy were included. Medication treatment for inappropriateness was assessed by using the MAI. Under-prescribing was also screened for.
Treatment charts of 125 patients, including 697 medications, were assessed using a MAI. Overall, 115 (92%) patients had one or more medications with one or more MAI criteria rated as inappropriate, giving a total of 384 (55.1%) medications prescribed inappropriately. The mean SD MAI score per drug was 1.78 (SD=2.19). The most common medication classes with appropriateness problems were biguanides (100%), anti-arrhythmics (100%) and anti-platelets (96.8%). The most common problems involved incorrect directions (26%) and incorrect dosages (18.5%). There were 36 omitted medications with untreated indications.
There is considerable inappropriate prescribing which could have significant negative effects regarding patient care.
在所有医学实践领域,合理用药仍然是一项重要的优先事项。
本研究的目的是应用药物适宜性指数(MAI)来识别急诊科(ED)收治患者中不合理用药的问题。
本研究在马耳他综合医院对125名患者进行,此前对10名患者进行了为期两周的试点。纳入年龄在18岁及以上且正在接受药物治疗的患者。使用MAI评估药物治疗的适宜性。同时也筛查了用药不足的情况。
使用MAI对125名患者的治疗图表进行了评估,其中包括697种药物。总体而言,115名(92%)患者有一种或多种药物的一项或多项MAI标准被评定为不适宜,共有384种(55.1%)药物的处方不合理。每种药物的平均标准差MAI评分为1.78(标准差=2.19)。存在适宜性问题的最常见药物类别是双胍类(100%)、抗心律失常药(100%)和抗血小板药(96.8%)。最常见的问题包括用药说明错误(26%)和剂量错误(18.5%)。有36种药物遗漏未治疗的适应证。
存在相当多的不合理用药情况,这可能对患者护理产生重大负面影响。