Department of Clinical Physiology, Lund University, Lund University Hospital Lund, Lund, Sweden.
J Cardiovasc Magn Reson. 2013 Oct 24;15(1):96. doi: 10.1186/1532-429X-15-96.
The effects on left and right ventricular (LV, RV) volumes during physical exercise remains controversial. Furthermore, no previous study has investigated the effects of exercise on longitudinal contribution to stroke volume (SV) and the outer volume variation of the heart. The aim of this study was to determine if LV, RV and total heart volumes (THV) as well as cardiac pumping mechanisms change during physical exercise compared to rest using cardiovascular magnetic resonance (CMR).
26 healthy volunteers (6 women) underwent CMR at rest and exercise. Exercise was performed using a custom built ergometer for one-legged exercise in the supine position during breath hold imaging. Cardiac volumes and atrio-ventricular plane displacement were determined. Heart rate (HR) was obtained from ECG.
HR increased during exercise from 60±2 to 94±2 bpm, (p<0.001). LVEDV remained unchanged (p=0.81) and LVESV decreased with -9±18% (p<0.05) causing LVSV to increase with 8±3% (p<0.05). RVEDV and RVESV decreased by -7±10% and -24±14% respectively, (p<0.001) and RVSV increased 5±17% during exercise although not statistically significant (p=0.18). Longitudinal contribution to RVSV decreased during exercise by -6±15% (p<0.05) but was unchanged for LVSV (p=0.74). THV decreased during exercise by -4±1%, (p<0.01) and total heart volume variation (THVV) increased during exercise from 5.9±0.5% to 9.7±0.6% (p<0.001).
Cardiac volumes and function are significantly altered during supine physical exercise. THV becomes significantly smaller due to decreases in RVEDV whilst LVEDV remains unchanged. THVV and consequently radial pumping increases during exercise which may improve diastolic suction during the rapid filling phase.
体力活动对左心室（LV）和右心室（RV）容积的影响仍存在争议。此外，以前没有研究调查过运动对SV 的纵向贡献以及心脏外容积变化的影响。本研究旨在使用心血管磁共振（CMR）确定与休息相比，LV、RV 和总心脏（TH）容积以及心脏泵机制是否在体力活动期间发生变化。
26 名健康志愿者（6 名女性）在休息和运动时接受 CMR。运动是在仰卧位使用定制的单腿运动测功计在屏气成像期间进行的。确定心脏容积和房室平面位移。从心电图获得心率（HR）。
运动时 HR 从 60±2 增加到 94±2 bpm（p<0.001）。LVEDV 保持不变（p=0.81），LVESV 减少-9±18%（p<0.05），导致 LVSV 增加 8±3%（p<0.05）。RVEDV 和 RVESV 分别减少-7±10%和-24±14%，（p<0.001），RVSV 在运动时增加 5±17%，尽管无统计学意义（p=0.18）。运动期间 RVSV 的纵向贡献减少了-6±15%（p<0.05），而 LVSV 不变（p=0.74）。运动期间 THV 减少 4±1%（p<0.01），THVV 增加 5.9±0.5%至 9.7±0.6%（p<0.001）。
仰卧体力活动期间心脏容积和功能明显改变。由于 RVEDV 的减少，THV 明显变小，而 LVEDV 保持不变。运动时 THVV 和径向泵增加，这可能会在快速充盈期改善舒张抽吸。
