Shikimi T
Jpn J Pharmacol. 1985 Aug;38(4):433-5. doi: 10.1254/jjp.38.433.
Both immunochemical and kinetic evidence suggest that the increase in aprotinin activity in the presence of heparin is not due to an increase in the active form of aprotinin, but rather to a qualitative change in the aprotinin molecule which would lead to an increase in aprotinin activity.
免疫化学和动力学证据均表明,在肝素存在的情况下抑肽酶活性的增加并非由于抑肽酶活性形式的增加,而是由于抑肽酶分子的性质变化,这会导致抑肽酶活性增加。