Galasso Rocco, Capocaccia Riccardo, Del Riccio Luciana, Viviano Lorena, Matera Rosa, Rossi Silvia
Tumori. 2013 May-Jun;99(3):390-8. doi: 10.1177/030089161309900315.
Basilicata and Calabria are two neighboring, low income regions of southern peninsular Italy with an overall population of about 2.5 million in 2010. Cancer registration has covered the entire Basilicata population since 2005 and the province of Catanzaro (18.3% of the Calabria population) since 2003. This paper will provide estimates and projections for the period 1970-2015 of the basic epidemiological indicators - incidence, prevalence and mortality - in the Basilicata and Calabria regions for the major cancers (lung, colon and rectum, stomach, skin mela-noma, breast, cervix and prostate).
The indicators were estimated by applying the MIAMOD statistical back-calculation method to the 1970-2002 official mortality data, and to the 1985-2002 relative survival data collected by population-based registries of the southern regions of Italy.
The incidence rates were estimated to be still rising for breast, prostate and colorectal cancer, and for skin melanoma in men. By contrast, they were estimated to be declining for cervix and stomach cancer. The incidence increased, reaching a peak, and subsequently decreased for lung cancer in men and for skin melanoma in women. The age-standardized mortality rates were estimated to decrease for all considered cancers except prostate cancer in men and lung cancer in women, which presented quite stable mortality rates from the mid 2000s onwards. Except for cervix cancer, prevalence was increasing for all considered cancers, particularly those of the breast and prostate.
These data support the need for health policies focused on primary and secondary prevention, which is the main way to reduce the overall impact of cancer and to preserve health care resources, as well as on actions aimed at ensuring equal access to cancer care and at transferring innovation into clinical practice.
巴西利卡塔和卡拉布里亚是意大利南部半岛相邻的两个低收入地区,2010年总人口约为250万。自2005年起癌症登记覆盖了巴西利卡塔的全部人口,自2003年起覆盖了科森扎省(卡拉布里亚人口的18.3%)。本文将提供1970 - 2015年期间巴西利卡塔和卡拉布里亚地区主要癌症(肺癌、结肠直肠癌、胃癌、皮肤黑色素瘤、乳腺癌、子宫颈癌和前列腺癌)的基本流行病学指标——发病率、患病率和死亡率的估计值与预测值。
通过将MIAMOD统计反向推算方法应用于1970 - 2002年官方死亡率数据以及意大利南部地区基于人群登记处收集的1985 - 2002年相对生存数据,来估计这些指标。
估计乳腺癌、前列腺癌、结肠直肠癌以及男性皮肤黑色素瘤的发病率仍在上升。相比之下,估计子宫颈癌和胃癌的发病率在下降。男性肺癌和女性皮肤黑色素瘤的发病率上升至峰值后随后下降。除男性前列腺癌和女性肺癌外,估计所有考虑的癌症的年龄标准化死亡率均在下降,自2000年代中期起,这两种癌症的死亡率相当稳定。除子宫颈癌外,所有考虑的癌症的患病率都在上升,尤其是乳腺癌和前列腺癌。
这些数据支持制定侧重于一级和二级预防的卫生政策的必要性(这是减少癌症总体影响和保护医疗资源的主要途径),以及采取旨在确保平等获得癌症治疗并将创新转化为临床实践的行动。