Laboratório de Microbiologia, Fundação Oswaldo Cruz, Rondônia-Fiocruz, Porto Velho, RO, CEP 78910-210, Brazil.
Arch Virol. 2014 May;159(5):1139-42. doi: 10.1007/s00705-013-1847-8. Epub 2013 Oct 25.
Rotavirus group A (RVA) infection was ascertained in 591 fecal samples from children 0 to 6 years old with acute gastroenteritis. The vaccination status was also verified in all 591 subjects, with 302 (51.0 % ± 4.0 %) participants fully vaccinated against rotavirus. Forty-two of the vaccinated children (13.9 % ± 3.9 %) tested positive for RVA infection. Of the 289 unvaccinated children (49.0 % ± 4.0 %), 61 (21.1 % ± 4.7 %) had stools positive for RVA. This study suggests that the proportion of acute diarrhea cases caused by rotavirus was low and that the incidence of rotavirus diarrhea decreased over the study period in both vaccinated and unvaccinated children.
591 份 0 至 6 岁急性肠胃炎患儿粪便样本中检测到轮状病毒 A 群(RVA)感染。所有 591 名受试者的疫苗接种情况也得到了证实,其中 302 名(51.0%±4.0%)儿童完全接种了轮状病毒疫苗。42 名接种疫苗的儿童(13.9%±3.9%)RVA 感染检测呈阳性。在 289 名未接种疫苗的儿童(49.0%±4.0%)中,61 名(21.1%±4.7%)粪便 RVA 检测呈阳性。本研究表明,轮状病毒引起的急性腹泻病例比例较低,且在接种和未接种疫苗的儿童中,轮状病毒腹泻的发病率在研究期间呈下降趋势。