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[感染性变应性支气管哮喘患者活动性炎症过程的标准]

[Criteria for the active inflammatory process in patients with infectious-allergic bronchial asthma].

作者信息

Petrov D

出版信息

Vutr Boles. 1985;24(4):80-6.

PMID:2416136
Abstract

A total of 114 patients with infections-allergic bronchial asthma were studied, being subdivided into two groups. The first group covers 53 patients without clinical, immunologic, X-ray, enzymatic and biochemical sings of active inflammation. The second group includes 61 patients with manifested bronchial-pulmonary inflammation. Immunoglobulins of classes IgA, IgM, and IgG, complement enzymatic activity of total acid phosphatase were studied as well as sorbitoldehydrogenase and "acute phase" proteins. The values of immunoglobulin classes IgA and IgG, coplement, enzymatic activity of total acid phosphatase and sorbitodechydrogenase and "acute phase" proteins were established to be with regularly increased values with high statistical significance. Those indices could serve the differentiation and making the diagnosis of acute and exacerbated pulmonary inflammation as well as for prescribing the adequate antiinflammatory treatment of the patients with infectious-allergic bronchial asthma.

摘要

共对114例感染性变应性支气管哮喘患者进行了研究,并将其分为两组。第一组包括53例无活动性炎症的临床、免疫、X线、酶学和生化体征的患者。第二组包括61例有明显支气管-肺部炎症的患者。研究了IgA、IgM和IgG类免疫球蛋白、总酸性磷酸酶的补体酶活性以及山梨醇脱氢酶和“急性期”蛋白。确定IgA和IgG类免疫球蛋白、补体、总酸性磷酸酶和山梨醇脱氢酶的酶活性以及“急性期”蛋白的值呈规律性升高,具有高度统计学意义。这些指标可用于感染性变应性支气管哮喘患者急性和加重期肺部炎症的鉴别和诊断,以及指导适当的抗炎治疗。

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